Clinical Trials in Dallas

Showing 3561-3580 of 15,003 trials

Acute Kidney Injury Genomics and Biomarkers in TAVR Study

NCT02791880

In the last decade, transcatheter aortic valve replacement (TAVR) has become an increasingly utilized alternative procedure for replacing a stenotic aortic valve. This study collects clinical information, DNA, blood and urine samples (throughout procedural hospitalization) in order to investigate the incidence of acute kidney injury (AKI) in patients undergoing TAVR and to identify key clinical and procedural predictors of AKI. This study seeks to identify blood and urine biomarkers that can be used for early detection of AKI around the time of the procedure. The study seeks to assess for novel genetic variants associated with development of AKI after TAVR. Finally the study seeks to assess for novel genetic variants and biomarkers that are associated with adverse cardiovascular events after TAVR and to further explore how these events may inter-relate with acute kidney injury.

Acute Kidney InjuryRenal Insufficiency, ChronicHeart Failure+3 more

University of Texas Southwestern Medical Center62 participantsStarted Oct 2016

Dallas, Texas, United States • Dallas, Texas, United States • Dallas, Texas, United States

COMPLETED< 1 mile

A Review of External Ventricular Drain Placement at the Bedside Versus Operating Room

NCT06139289

External ventricular drain (EVD) placement is a common neurosurgical procedure and provides a way to monitor intracranial pressure. EVDs are utilized in the management of a wide array of neurosurgical indications, such as subarachnoid hemorrhage, trauma, intraventricular hemorrhage, cerebrospinal fluid (CSF) leaks, and hydrocephalus.

External Ventricular Drain

Methodist Health System200 participantsStarted Sep 2022

Dallas, Texas, United States

COMPLETEDPhase 2< 1 mile

A Study of LY3372689 to Assess the Safety, Tolerability, and Efficacy in Participants With Alzheimer's Disease

NCT05063539

The purpose of this study is to assess the safety, tolerability and effect of study drug LY3372689 in participants with early symptomatic Alzheimer's Disease

Alzheimer Disease

Eli Lilly and Company327 participantsStarted Sep 2021

Canoga Park, California, United States • Fresno, California, United States • Irvine, California, United States +66 more locations

Acute Kidney Injury Genomics and Biomarkers in TAVR Study

A Review of External Ventricular Drain Placement at the Bedside Versus Operating Room

A Study of LY3372689 to Assess the Safety, Tolerability, and Efficacy in Participants With Alzheimer's Disease

Find Trials by Condition in Dallas

Study of Obeldesivir to Treat Nonhospitalized Adults With Acute Respiratory Syncytial Virus (RSV) Infection

Study of Subcutaneous Epcoritamab in Combination With Intravenous Rituximab and Oral Lenalidomide (R2) to Assess Adverse Events and Change in Disease Activity in Adult Participants With Follicular Lymphoma

Evaluation of Intravenous Fluid Therapy Within Dallas Acute Pancreatitis Protocol

A Study to Evaluate Safety and Tolerability of CVL-231 (Emraclidine) in Adult Participants With Schizophrenia

Efficacy, Safety, and Pharmacokinetics of Sugammadex (MK-8616) for Reversal of Neuromuscular Blockade in Pediatric Participants Aged Birth to <2 Years (MK-8616-169)

Safety and Efficacy of Hectorol in Pediatric Patients With Chronic Kidney Disease Stage 3 and 4 With Secondary Hyperparathyroidism Not Yet on Dialysis

Open-Label Surufatinib in European Patients With NET

QTX3046 in Patients With KRAS G12D Mutations

Donor-Derived Anti-CD33 CAR T Cell Therapy (VCAR33) in Patients With Relapsed or Refractory AML After Allogeneic Hematopoietic Cell Transplant

A Long-term Follow-up Study of Patients Who Received VOR33

Ceribell Delirium Data Collection Study

First-in-human Study of MRT-6160 in Healthy Subjects

Specialty Compared to Oncology Delivered Palliative Care for Patients With Acute Myeloid Leukemia

Trial of ARV-110 and Abiraterone in Patients With Metastatic Castration Resistant Prostate Cancer (mCRPC)

Prospective, Open-label, Non-significant Risk, Multicenter Study Comparing the Polyp Detection of the Study Device to That of the Colonoscopy Reference

A Study of Sequential Therapy With Daplusiran/Tomligisiran (DAP/TOM) Followed by Bepirovirsen in Participants Living With Chronic Hepatitis B (CHB)

TURN-IT FOG: Improving Turning and Freezing of Gait in People With PD