Clinical Trials in Cleveland

Showing 6781-6800 of 19,775 trials

A Randomized Phase 2 Trial of TAS-114 in Combination With S-1 Versus S-1

NCT02855125

This is a randomized, open-label, Phase 2 study of TAS-114 administered in combination with S-1, to investigate the efficacy, safety and tolerability of the TAS-114/S-1 regimen in patients with advanced or metastatic NSCLC. The study will be conducted internationally in 2 regions: Asian \[Japan\] and Western \[Europe and US\]. Patients will be randomized into TAS-114/S-1 arm versus S-1 control arm in a 1:1 ratio.

Advanced or Metastatic Non-small Cell Lung Cancer

Taiho Oncology, Inc.128 participantsStarted Aug 2016

Loma Linda, California, United States • Gainesville, Florida, United States • Cleveland, Ohio, United States +27 more locations

COMPLETEDPhase 3< 1 mile

Study to Assess Efficacy and Safety of Cx601, Adult Allogeneic Expanded Adipose-derived Stem Cells (eASC) for the Treatment of Complex Perianal Fistula(s) in Participants With Crohn's Disease (CD)

NCT03279081

The purpose of this study is to evaluate the combined remission of complex perianal fistulas, defined as the clinical assessment at Week 24 of closure of all treated external openings that were draining at baseline despite gentle finger compression, and absence of collections greater than (\>) 2 centimeter (cm) (in at least 2 dimensions) confirmed by blinded central magnetic resonance imaging (MRI) assessment at Week 24.

Crohn's Disease

Tigenix S.A.U.568 participantsStarted Sep 2017

Scottsdale, Arizona, United States • La Jolla, California, United States • Los Angeles, California, United States +156 more locations

A Randomized Phase 2 Trial of TAS-114 in Combination With S-1 Versus S-1

Study to Assess Efficacy and Safety of Cx601, Adult Allogeneic Expanded Adipose-derived Stem Cells (eASC) for the Treatment of Complex Perianal Fistula(s) in Participants With Crohn's Disease (CD)

Find Trials by Condition in Cleveland

IMP4297 in Combination With Temozolomide in Patients With Advanced Solid Tumors and Small Cell Lung Cancer

A Study of Atezolizumab as Neoadjuvant and Adjuvant Therapy in Resectable Non-Small Cell Lung Cancer (NSCLC) - Lung Cancer Mutation Consortium (LCMC3)

An Open-Label Extension Study for Patients With Duchenne Muscular Dystrophy Who Participated in Studies of SRP-5051 (Vesleteplirsen)

Health Outcomes of Parents With Cystic Fibrosis

Clinical Evaluation of the i-STAT TBI Test

The CAPTURE Study: Validating a Unique COPD Case Finding Tool in Primary Care (Aim 3)

Long-term Safety of Lumacaftor/Ivacaftor in Participants With Cystic Fibrosis Who Are Homozygous for F508del and 12 to <24 Months of Age at Treatment Initiation

A Phase 2 Study to Evaluate the Efficacy and Safety of VIR-2482 for the Prevention of Illness Due to Influenza A

Breast Cancer Index (BCI) Registry

Strategies to Assist With Management of Pain

Electrical Vestibular Nerve Stimulation (VeNS) Compared to Sham Control As a Means of Improving Glycemic Control in Adults with Type 2 Diabetes Mellitus

Umbilical Cord Milking in Non-Vigorous Infants

A Safety and Efficacy Study in Patients With Gastric Cancer

Study to Evaluate Treatment Compliance, Efficacy and Safety of an Improved Deferasirox Formulation (Granules) in Pediatric Patients (2-<18 Years Old) With Iron Overload

Phase 1, First-in-human Study of Oral TP-1287 in Patients with Advanced Solid Tumors

Viz HCM (ECG Assist) Utilization Workflow Pilot

Peer Mentorship to Improve Outcomes in Patients on Maintenance Hemodialysis

A Phase I/II Trial Investigating LOAd703 in Combination With Atezolizumab in Malignant Melanoma