Clinical Trials in Cleveland

Showing 6001-6020 of 19,775 trials

Transition From Basal/Bolus to Once-weekly Subcutaneous Semaglutide and Basal Insulin in Patients With T2D

NCT04538352

This study is designed to determine whether therapy with once-weekly sc semaglutide in combination with once-daily insulin degludec will be capable of maintaining (or improving) glycemic control, when substituted for multiple daily injections of insulin (MDI), in patients with T2D with adequate glycemic control (≤ 7.5%) on MDI-based regimens (≤ 80 units of insulin per day), vs. further titration of insulin therapy in those continuing MDI. Weight loss, hypoglycemic episodes, and improvement in diabetes-treatment satisfaction will also be assessed between the two groups.

Type 2 Diabetes

The Cleveland Clinic60 participantsStarted Jan 2021

Cleveland, Ohio, United States

WITHDRAWNEARLY Phase 1< 1 mile

Study Evaluating the Safety of Myeliviz Myelin-Targeting PET Agent

NCT04333290

This study evaluates the safety of \[11C\]MeDAS, a PET radiotracer.

Healthy

Robert FoxStarted Jul 2024

Cleveland, Ohio, United States

COMPLETEDNA< 1 mile

Safety and Effectiveness of the MiniMed™ 780G System With DS5 CGM

NCT05714059

The purpose of this study is to confirm the safety and effectiveness of the MiniMed 780G insulin pump used in combination with the DS5 CGM in type 1 diabetes adult and pediatric subjects in a home setting.

Type 1 Diabetes

Medtronic MiniMed, Inc.250 participantsStarted Feb 2023

Little Rock, Arkansas, United States • Palo Alto, California, United States • San Francisco, California, United States +20 more locations

Transition From Basal/Bolus to Once-weekly Subcutaneous Semaglutide and Basal Insulin in Patients With T2D

Study Evaluating the Safety of Myeliviz Myelin-Targeting PET Agent

Safety and Effectiveness of the MiniMed™ 780G System With DS5 CGM

Find Trials by Condition in Cleveland

A Study of KB-0742 in Participants With Relapsed or Refractory Solid Tumors Including Platinum Resistant High Grade Serous Ovarian Cancer (HGSOC)

RAD001 and Neurocognition in PTEN Hamartoma Tumor Syndrome

NovoTTF-100A With Bevacizumab (Avastin) in Patients With Recurrent Glioblastoma

Study of the Efficacy of Lurasidone in Cognitive Functioning in Bipolar Patients

Using Calcium Hydroxylapatite To Treat Gum Recession and Tooth Hypersensitivity

A Study to Assess the Safety, Tolerability and Efficacy of IONIS-AGT-LRx in Hypertensive Participants With Uncontrolled Blood Pressure

INFINITY™Total Ankle Replacement Follow-up

Neuroblastoma Precision Trial

A Safety, Tolerability, and Efficacy Study of BMN 190 in Pediatric Patients < 18 Years of Age With CLN2 Disease

BioProtect Balloon Implant™ Balloon System Pivotal Study BP-007

Mapping the Genotype, Phenotype, and Natural History of Phelan-McDermid Syndrome

Evaluation of the Safety and Effectiveness of Bilateral Exablate Ablation of the Pallidothalamic Tract (PTT) for the Treatment of the Motor Complications of Parkinson's Disease (PD)

P-PSMA-101 CAR-T Cells in the Treatment of Subjects With Metastatic Castration-Resistant Prostate Cancer (mCRPC) and Advanced Salivary Gland Cancers (SGC)

A Study to Assess the Pharmacodynamics of VK0214 in Male Subjects With AMN

Study of Daily Application of Nestorone® (NES) and Testosterone (T) Combination Gel for Male Contraception

A Phase 1b Study of Imvotamab in Moderate to Severe Rheumatoid Arthritis

MCT for the Harvard/UCSF ROBIN Center