Clinical Trials in Cleveland

Showing 5461-5480 of 19,775 trials

Study of Cytokine Release Syndrome Prophylaxis and Treatment With Siltuximab Prior to Epcoritamab

NCT06447376

The goal of this clinical trial is to is to determine the safety, feasibility and efficacy of siltuximab prophylaxis of cytokine release syndrome and neurotoxicity occurring after epcoritamab subcutaneous administration for participants with large b-cell lymphoma (DLBCL) or follicular lymphoma (FL). Participants will receive siltuximab, prior to the injection of epcoritamab. Epcoritamab is administered in 28 day cycles for one year. After this injection, the physician will continue to watch participants for side effects and follow the condition for a minimum of 60 days.

Non-Hodgkin LymphomaCytokine Release Syndrome

Taylor Brooks20 participantsStarted Jan 2025

Cleveland, Ohio, United States

COMPLETEDNA< 1 mile

Unrelated Donor Transplant Versus Immune Therapy in Pediatric Severe Aplastic Anemia

NCT02845596

The purpose of this study is to determine the feasibility of comparing outcomes of patients treated de novo with immunosuppressive therapy (IST) versus matched unrelated donor (MUD) hematopoietic stem cell transplant (HSCT) for pediatric acquired severe aplastic anemia.

Severe Aplastic Anemia

Michael Pulsipher40 participantsStarted Aug 2016

Los Angeles, California, United States • Palo Alto, California, United States • San Francisco, California, United States +10 more locations

Study of Cytokine Release Syndrome Prophylaxis and Treatment With Siltuximab Prior to Epcoritamab

Unrelated Donor Transplant Versus Immune Therapy in Pediatric Severe Aplastic Anemia

Find Trials by Condition in Cleveland

A Study of Trastuzumab Deruxtecan (T-DXd) Versus Trastuzumab Emtansine (T-DM1) in High-risk HER2-positive Participants With Residual Invasive Breast Cancer Following Neoadjuvant Therapy (DESTINY-Breast05)

Phase 2 Study to Assess Efficacy & Safety of WP1302 Prevent Relapse of MMI w/Draw in Subj. w/ Graves' dz

APVO436 Phase 1b/2 Study in Patients With Newly Diagnosed AML

Study of TVB-2640 in Subjects With Nonalcoholic Steatohepatitis (NASH)

Study of Carfilzomib, Daratumumab and Dexamethasone for Patients With Relapsed and/or Refractory Multiple Myeloma.

Study of Adagloxad Simolenin (OBI-822)/OBI-821 in the Adjuvant Treatment of Patients With Globo H Positive TNBC

PRV-3279-2a Trial in Systemic Lupus

Sequenced Treatment Effectiveness for Posttraumatic Stress

A Research Study To See How Well an Eye Drop, SURF-100 (A Mycophenolic Acid/Betamethasone Sodium Phosphate Combination), Works and What Side Effects There Are in Subjects With Dry Eye Disease

A Phase 2 Biomarker - Enriched Study of TH-302 in Subjects With Advanced Melanoma

A 24 Week Trial to Compare the Efficacy and Safety of Delgocitinib Cream 20 mg/g Twice-daily With Alitretinoin Capsules Once-daily in Adult Participants With Severe Chronic Hand Eczema

Antiviral Cellular Therapy for Enhancing T-cell Reconstitution Before or After Hematopoietic Stem Cell Transplantation

Evaluating the Safety and Effectiveness of the InnAVasc Graft for Dialysis Access in Patients With Kidney Failure

Adalimumab in JIA-associated Uveitis Stopping Trial

Efficacy in iNPH Shunting (PENS) Trial

M-Vizion™ Macroscopic Radiographic Study

Trauma Informed Guilt Reduction Therapy

SIRT Followed by CIS-GEM Chemotherapy Versus CIS-GEM Chemotherapy Alone as 1st Line Treatment of Patients With Unresectable Intrahepatic Cholangiocarcinoma