Clinical Trials in Cleveland

Showing 5321-5340 of 19,775 trials

CLOSM Trial: Groin Closure Using Layered Option for Suture Material

NCT06990425

This is a randomized controlled trial comparing groin closure after vascular intervention with Vicryl suture versus PDS (polydioxanone) suture. This will be a single center trail performed at CCF main campus. Patients will be enrolled in a prospective fashion and will be randomized 1:1 to either PDS or Vicryl closure. Patients undergoing bilateral groin exposure will be randomized to receive both closure types to either groin.

Vascular Diseases

The Cleveland Clinic259 participantsStarted Mar 2025

Cleveland, Ohio, United States

TERMINATEDPhase 1/2< 1 mile

Safety and Tolerability of M254 in Healthy Volunteers and Immune Thrombocytopenic Purpura (ITP) Patients

NCT03866577

The purpose of this study is to assess safety, tolerability, pharmacokinetics, and pharmacodynamics of M254 after administration of a single ascending dose and repeat doses in healthy volunteers and immune thrombocytopenic purpura (ITP) patients. The pharmacodynamics of the drug will be measured as platelet response in patients with ITP.

Immune Thrombocytopenic Purpura (ITP)

Momenta Pharmaceuticals, Inc.50 participantsStarted Dec 2018

Los Angeles, California, United States • Whittier, California, United States • Miami Lakes, Florida, United States +25 more locations

CLOSM Trial: Groin Closure Using Layered Option for Suture Material

Safety and Tolerability of M254 in Healthy Volunteers and Immune Thrombocytopenic Purpura (ITP) Patients

Find Trials by Condition in Cleveland

RTA 402 in Patients With Advanced Solid Tumors or Lymphoid Malignancies

Assessment of Safety and Effectiveness in Treatment Management of Atrial Fibrillation With the BWI IRE Ablation System

Ruxolitinib Phosphate, Paclitaxel, and Carboplatin in Treating Patients With Stage III-IV Epithelial Ovarian, Fallopian Tube, or Primary Peritoneal Cancer

Simufilam 100 mg for Mild-to-Moderate Alzheimer's Disease

Evaluating SUI-100™, A Non-Invasive Device for the Treatment of Stress Urinary Incontinence

Low Dose Ketamine Infusion for Analgesia in the Emergency Department to Reduce Side Effects

A Study of Intravenous L-Citrulline in Patients Aged 6-21 Years Old With Sickle Cell Disease Presenting to Emergency Departments in Acute Vaso-Occlusive Crisis

Safety and Efficacy of Tideglusib in Congenital or Childhood Onset Myotonic Dystrophy

SPIROMICS Study of Early COPD Progression (SOURCE)

A Study to Evaluate the Efficacy and Safety of Daratumumab in Pediatric and Young Adult Participants Greater Than or Equal to (>=)1 and Less Than or Equal to (<=) 30 Years of Age With Relapsed/Refractory Precursor B-cell or T-cell Acute Lymphoblastic Leukemia or Lymphoblastic Lymphoma

A Study to Investigate Efficacy and Safety of OG-6219 BID in 3 Dose Levels Compared With Placebo in Participants Aged 18 to 49 With Moderate to Severe Endometriosis-related Pain

A Study of CAP-1002 in Ambulatory and Non-Ambulatory Patients With Duchenne Muscular Dystrophy

Multi-Center Clinical Database of Infants for the Investigation of Early Nutrition Biomarkers

A Study of Ad26.COV2.S and Influenza Vaccines in Healthy Adults

Study With Gemcitabine and RTA 402 for Patients With Unresectable Pancreatic Cancer

A Study to Evaluate a Range of Dose Levels of an Adenovirus Serotype 26 (Ad26.RSV.preF)-Based Vaccine in Older Adults

An Open-Label Multiple Dose Study of RZ358 in Patients With Congenital Hyperinsulinism

HbA1c Variation Study