Clinical Trials in Cleveland

Showing 4381-4400 of 19,775 trials

Cross-Seal Closure Device IDE Trial - Study of the Cross-SealTM Suture-Mediated Vascular Closure Device System

NCT03756558

This study evaluates the safety and effectiveness of the Cross-Seal vascular closure device in gaining post procedure hemostasis in subjects undergoing interventional procedures requiring an 8 to 18 french size introducer sheath.

Vascular Closure

Terumo Medical Corporation147 participantsStarted Aug 2019

Denver, Colorado, United States • Jacksonville, Florida, United States • Tampa, Florida, United States +17 more locations

Active Not RecruitingPhase 3< 1 mile

S1803, Lenalidomide +/- Daratumumab/rHuPh20 as Post-ASCT Maintenance for MM w/MRD to Direct Therapy Duration

NCT04071457

Patients are enrolled to screening (Reg Step 1) prior to or after ASCT but prior to Reg Step 2. Patients are followed until they will begin Maintenance and then registered to Reg Step 2 (first randomization). Patients are randomized between Lenalidomide for 2 years and Lenalidomide + Daratumumab/rHuPH20. After 2 years of Maintenance, MRD is assessed to guide further therapy. MRD-positive patients will continue with the assigned treatment. MRD-negative patients will be further randomized (Reg Step 3) to either continue or discontinue the assigned treatment. Patients are treated for up to 7 years from Step 2 reg and followed for up to 15 years.

Multiple Myeloma

SWOG Cancer Research Network1,100 participantsStarted Aug 2019

Anchorage, Alaska, United States • Anchorage, Alaska, United States • Anchorage, Alaska, United States +839 more locations

Cross-Seal Closure Device IDE Trial - Study of the Cross-SealTM Suture-Mediated Vascular Closure Device System

S1803, Lenalidomide +/- Daratumumab/rHuPh20 as Post-ASCT Maintenance for MM w/MRD to Direct Therapy Duration

Find Trials by Condition in Cleveland

Study to Evaluate SAGE-547 Injection as Adjunctive Therapy for the Treatment of Super-Refractory Status Epilepticus

Safety Study of a Vaccine to Help Protect Against Lyme Disease in Healthy Children

A Study to Evaluate the Effect of SAGE-718 on Cognitive Function in Participants With Huntington's Disease (HD)

Real-World Effectiveness of Dupilumab in Patients With Prurigo Nodularis: An Observational Study

Veliparib and Topotecan Hydrochloride in Treating Patients With Solid Tumors, Relapsed or Refractory Ovarian Cancer, or Primary Peritoneal Cancer

NANT 2015-02: A Phase 1 Study of Lorlatinib (PF-06463922)

The Use of Mentoring to Promote Well-being for Female SMART Members

28-Day Study of SAGE-718 on Functioning Capacity in Participants With Huntington's Disease

Treatment Monitoring in Autism Spectrum Disorder (ASD) in Children

A First-in-human Study Using BDC-1001 as a Single Agent and in Combination With Nivolumab in Advanced HER2-Expressing Solid Tumors

Pharmacodynamic EffIcacy and Clinical Benefit of AT 007 in Patients With Sorbitol Dehydrogenase (SORD) Deficiency

Locking Plates for Distal Femur Fractures - a Multicenter Case Review

BlueWind RENOVA iStim™ System for the Treatment of OAB

PRO 140 in Treatment-Experienced HIV-1 Subjects

A Study in Adults to Investigate the Impact of Mild, Moderate, and Severe Hepatic Impairment on Pharmacokinetics of Venglustat Compared to Participants With Normal Hepatic Function

Veterans Response to Dosage in Chiropractic Therapy

Janssen Ad26.CoV2.S Vaccine Booster in Kidney Transplant Recipients

Dupilumab-PEdiatric Skin Barrier Function and LIpidomics STudy in Patients With Atopic Dermatitis