Clinical Trials in Cleveland

Showing 4301-4320 of 19,775 trials

Physiological Effects Ketone Ester in Heart

NCT05924802

The study is aimed to phenotype with cardiac MRI the physiological effects of ketone esters on the heart. Patients with heart failure will be recruited and given ketone esters or placebo in a randomized fashion. Cardiac MRI will be performed at baseline and after 12weeks follow up.

Heart Failure

The Cleveland Clinic50 participantsStarted Jun 2024

Cleveland, Ohio, United States

COMPLETEDPhase 3< 1 mile

A Study Evaluating the Long-term Safety and Efficacy of VX-445 Combination Therapy

NCT03525574

The study evaluates the long-term safety and tolerability of VX-445 in triple combination (TC) with tezacaftor (TEZ) and ivacaftor (IVA) in subjects with cystic fibrosis (CF) who are homozygous or heterozygous for the F508del mutation

Cystic Fibrosis

Vertex Pharmaceuticals Incorporated507 participantsStarted Oct 2018

Tucson, Arizona, United States • Little Rock, Arkansas, United States • Long Beach, California, United States +107 more locations

Physiological Effects Ketone Ester in Heart

A Study Evaluating the Long-term Safety and Efficacy of VX-445 Combination Therapy

Find Trials by Condition in Cleveland

CAB-AXL-ADC Safety and Efficacy Study in Adult and Adolescent Patients With Sarcoma

Transplant Navigator Intervention to Overcome Barriers to Kidney Transplantation

Evaluate the Safety, Efficacy, and Pharmacokinetics of CRN04894 in Participants With Congenital Adrenal Hyperplasia (TouCAHn)

UF-KURE-BCMA CAR-T Cells in Patients With Relapsed or Refractory Multiple Myeloma

A Study to Evaluate the Efficacy and Safety of BLI5100 in Patients With Erosive Esophagitis

A Dose Escalation Study of HBI-2438 in Patients With Solid Tumors Harboring KRAS G12C Mutation

A Dose Escalation Study of SHP2 Inhibitor in Patients With Solid Tumors Harboring KRAS of EGFR Mutations

A Study of AZD3427 in Participants With Heart Failure and Pulmonary Hypertension Group 2

Study on Two Adjuvanted Dose Levels of Panblok H7+MF59 Compared for Immunogenicity and Safety With an Unadjuvanted Dose of Panblok H7 in Participants 18 Years of Age and Older

Study to Evaluate Safety and Efficacy of VX-661 in Combination With Ivacaftor in Subjects With Cystic Fibrosis, Homozygous for the F508del-CFTR Mutation With an Open-Label Expansion

Weight Bearing After Pelvis and Acetabulum Fracture Fixation

A Study Testing the Use of a Perivascular Sirolimus Formulation (Sirogen) in ESRD Patients Undergoing AV Fistula Surgery

Study of Lenacapavir and Emtricitabine/Tenofovir Disoproxil Fumarate (F/TDF) in Prevention of HIV in Cisgender Women in the United States (HPTN 102)

Metabolic Mechanisms Induced by Enteral DHA and ARA Supplementation in Preterm Infants

Computerized Registry of Patients With Venous Thromboembolism (RIETE)

An Extension Study to Evaluate Safety and Efficacy in Participants Treated With CRN04894

A Study to Evaluate ELX/TEZ/IVA on Cough and Physical Activity in Participants With Cystic Fibrosis (CF)

Phase1/2a Study for IPG7236 in Patients With Advanced Solid Tumors