Clinical Trials in Cleveland

Showing 2581-2600 of 16,969 trials

The Impact of Exercise on Subthalamic Nucleus Neural Activity in Parkinson's Disease

NCT05905302

Fifteen PwPD who have undergone DBS surgery and utilize the Percept system will complete a FE and VE exercise session on a stationary cycle while Off antiparkinsonian medication. Bilateral neural activity of the STN will be continuously recorded for 130 minutes (pre-, during FE or VE and post-exercise). The Movement Disorders Society Unified Parkinson's Disease Rating Scale (MDS-UPDRS) III Motor Exam and upper extremity force-tracking task will be used to determine motor response to exercise.

Parkinson DiseaseDeep Brain Stimulation

Jay Alberts15 participantsStarted Aug 2023

Cleveland, Ohio, United States

COMPLETEDPhase 4< 1 mile

Study of Ketorolac Versus Opioid for Pain After Endoscopy

NCT03888144

A double blind randomized controlled trial designed to compare pain control and safety with ketorolac and oxycodone in the post-operative setting for patients undergoing ureteroscopy for treatment of urinary stones. Patients are followed for five days after their surgery as they record their pain scores, medication utilization, and stent related symptoms.

Kidney CalculiUreteral Calculi

The Cleveland Clinic81 participantsStarted Oct 2017

Cleveland, Ohio, United States

Active Not RecruitingPhase 3< 1 mile

Durvalumab With or Without Olaparib as Maintenance Therapy After First-Line Treatment of Advanced and Recurrent Endometrial Cancer

NCT04269200

A study to assess the efficacy and safety of durvalumab in combination with platinum-based chemotherapy (paclitaxel + carboplatin) followed by maintenance durvalumab with or without olaparib for patients with newly diagnosed advanced or recurrent endometrial cancer.

Endometrial Neoplasms

AstraZeneca805 participantsStarted May 2020

Tucson, Arizona, United States • Concord, California, United States • La Jolla, California, United States +199 more locations

The Impact of Exercise on Subthalamic Nucleus Neural Activity in Parkinson's Disease

Study of Ketorolac Versus Opioid for Pain After Endoscopy

Durvalumab With or Without Olaparib as Maintenance Therapy After First-Line Treatment of Advanced and Recurrent Endometrial Cancer

Find Trials by Condition in Cleveland

A Study of Ocrelizumab in Children and Adolescents With Relapsing-Remitting Multiple Sclerosis

A Study of Axicabtagene Ciloleucel in Participants With Relapsed/Refractory Indolent Non-Hodgkin Lymphoma

A Study to Evaluate Upadacitinib in Combination With Topical Corticosteroids in Adolescent and Adult Participants With Moderate to Severe Atopic Dermatitis

A Study to Evaluate Patient Satisfaction With the Overall Face and Neck Appearance After Combined Treatment of OnabotulinumtoxinA, JUVÉDERM® Products, KYBELLA, CoolSculpting Elite and SkinMedica Products

Study of Seladelpar in Participants With Primary Biliary Cholangitis (PBC)

Combination Trial of Tipifarnib and Alpelisib in Adult Recurrent/ Metastatic Head and Neck Squamous Cell Carcinoma (R/M HNSCC)

CPX-351 for the Treatment of Secondary Acute Myeloid Leukemia in Patients Younger Than 60 Years Old

Ribociclib and Letrozole Treatment in Ovarian Cancer

A Study of VRC07-523LS, PGT121.414.LS, and PGDM1400LS Broadly Neutralizing Monoclonal Antibodies Given Intravenously in Adult Participants Without HIV

Study of Efficacy and Safety of LNP023 in Primary IgA Nephropathy Patients

Study of the CycloPen Micro-Interventional System and Long-Term Clinical Outcomes

INCB000928 Administered as a Monotherapy or in Combination With Ruxolitinib in Participants With Anemia Due to Myeloproliferative Disorders

Phase 2 Study of MGL-3196 in Patients With Non-Alcoholic Steatohepatitis (NASH)

Study of Orally Administered MOMA-313 in Participants With Advanced or Metastatic Solid Tumors

Study of SX-682 Alone and in Combination With Oral or Intravenous Decitabine in Subjects With Myelodysplastic Syndrome

SP Thoracic IDE Study

Gene Therapy for Cardiomyopathy Associated With Friedreich's Ataxia