Clinical Trials in Cleveland

Showing 2241-2260 of 16,969 trials

JAB-30355 in Patients With Advanced Solid Tumors Harboring TP53 Y220C Mutation

NCT06386146

This study is to evaluate the efficacy and safety of JAB-30355 in adult participants with advanced solid tumors harboring TP53 Y220C mutation.

Solid Tumors

Jacobio Pharmaceuticals Co., Ltd.144 participantsStarted Jul 2024

Denver, Colorado, United States • Lake Mary, Florida, United States • St Louis, Missouri, United States +10 more locations

Active Not RecruitingPhase 1< 1 mile

A Study of PF-08046052/SGN-EGFRd2 in Advanced Solid Tumors

NCT05983133

This study will test the safety of a drug called PF-08046052/SGN-EGFRd2 in participants with advanced solid tumors. It will also study the side effects of this drug. A side effect is anything a drug does to the body besides treating the disease. Participants will have cancer that cannot be removed (unresectable) or has spread through the body (metastatic). This study will have three parts. Parts A and B of the study will find out how much PF-08046052/SGN-EGFRd2 should be given to participants. Part C will use the dose found in parts A and B to find out how safe PF-08046052/SGN-EGFRd2 is and if it works to treat solid tumor cancers.

Colorectal NeoplasmsCarcinoma, Non-Small-Cell LungSquamous Cell Carcinoma of the Head and Neck+1 more

Seagen, a wholly owned subsidiary of Pfizer65 participantsStarted Nov 2023

Los Angeles, California, United States • Los Angeles, California, United States • Santa Monica, California, United States +21 more locations

JAB-30355 in Patients With Advanced Solid Tumors Harboring TP53 Y220C Mutation

A Study of PF-08046052/SGN-EGFRd2 in Advanced Solid Tumors

Find Trials by Condition in Cleveland

Evaluating the Long-Term Safety and Tolerability of Efgartigimod PH20 SC Administered Subcutaneously in Patients With Generalized Myasthenia Gravis

DBT Skills Groups for Veterans at High Risk for Suicide Attempt

Clinical Transcriptomics in Systemic Vasculitis (CUTIS)

One-Time DNA Study for Vasculitis

Fulvestrant and/or Anastrozole in Treating Postmenopausal Patients With Stage II-III Breast Cancer Undergoing Surgery

A Research Study to See How Well CagriSema Compared to Semaglutide, Cagrilintide and Placebo Lowers Blood Sugar and Body Weight in People With Type 2 Diabetes Treated With Metformin With or Without an SGLT2 Inhibitor

A Phase 1 Study in Patients With HPV16+ Recurrent/ Metastatic Head and Neck Squamous Cell Carcinoma

US IDE Study of the Contour NEurovasCular System™ for IntraCranial Aneurysm Repair

A Study to Evaluate the Safety, Efficacy, PK, PD and Immunogenicity of Cipaglucosidase Alfa/Miglustat in IOPD Subjects Aged 0 to <18

Combination of GNS561 and Trametinib in Patients With Advanced KRAS Mutated Cholangiocarcinoma

Robotic Minimally Invasive Inguinal Hernia Repair Post-Market Clinical Study With the DEXTER Robotic System

Equity in Modifying Plaque Of WomEn With UndeRtreated Calcified Coronary Artery Disease

Study of [68Ga]FAPI-46 PET in Patients With Pancreatic Ductal Carcinoma

Nivolumab + Docetaxel + ADT in mHSPC Patients With DDRD or Inflamed Tumors

A Study of TAK-500 With or Without Pembrolizumab in Adults With Select Locally Advanced or Metastatic Solid Tumors

Avo In R/R And Previously Untreated MCL

A Study to Assess the Efficacy and Safety of HMI-115 in Subjects With Endometriosis-Associated Pain

A Study to Test Whether Different Combinations of BI 765063, Ezabenlimab, Chemotherapy, Cetuximab, and BI 836880 Help People With Head and Neck Cancer or Liver Cancer