Clinical Trials in Chicago

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A Randomized, Controlled Trial of Ganaxolone in Patients With Infantile Spasms

NCT00441896

The study consists of cohorts where participants are randomized, in a 2:1 ratio, to 1 of 2 sequences, A and B. In each cohort, Sequence A, comprised of participants, who will receive ascending doses of ganaxolone and ascending doses of placebo. Sequence B, comprised of participants, who will receive ascending doses of placebo and ascending doses of ganaxolone. The dosing level in each subsequent cohort will be based upon experience gained from previous cohorts.

Infantile Spasms

Marinus Pharmaceuticals57 participantsStarted Jan 2007

Los Angeles, California, United States • Los Angeles, California, United States • Washington D.C., District of Columbia, United States +12 more locations

TERMINATEDNA2.2 miles

TMS for Investigating Memory Facilitation

NCT05462782

The aim of this study is to investigate the effects of Transcranial Magnetic Stimulation (TMS) following a Paired Associative Stimulation (PAS) protocol on the memorization capacity of elderly individuals. For this purpose, we will apply TMS synchronized with a working memory (WM) task and assess its effects on cortical connectivity and memorization capacity by Magnetic Resonance Imaging (MRI) and WM task learning. This study will be carried out in an older population of healthy participants. We will use the study results to refine the task related PAS protocol towards enhancing memory performance and brain connectivity.

Age-associated Memory Impairment

Shirley Ryan AbilityLab1 participantsStarted Aug 2022

Chicago, Illinois, United States

A Randomized, Controlled Trial of Ganaxolone in Patients With Infantile Spasms

TMS for Investigating Memory Facilitation

Find Trials by Condition in Chicago

Genetic Analysis-Guided Dosing of FOLFIRABRAX in Treating Patients With Advanced Gastrointestinal Cancer

Feasibility of At-Home Handheld Spirometry

HLT® Meridian® TAVR Valve System Early Feasibility Study for Aortic Regurgitation

Convalescent Plasma to Limit SARS-CoV-2 Associated Complications

A Study of Nivolumab or Nivolumab Plus Experimental Medication BMS-986205 With or Without Bacillus Calumette-Guerin (BCG) in BCG Unresponsive Bladder Cancer That Has Not Invaded Into the Muscle Wall of the Bladder

A Study to Evaluate the Pharmacokinetics, Safety, and Tolerability of Immune Globulin (Human) 10% (Gamunex-C) PEG Process (IVIG-PEG) Compared to Gamunex-C in Participants With Primary Humoral Immunodeficiency

Pharmacokinetics and Safety of Ceftobiprole in Neonates and Infants up to 3 Months Treated With Systemic Antibiotics

A Phase 4 Study of Efficacy and Safety of Apremilast in Subjects With Moderate Plaque Psoriasis.

An Study of Patidegib Topical Gel, 2%, for the Reduction of Disease Burden of Persistently Developing Basal Cell Carcinomas in Patients With Non-Gorlin High Frequency BCC

A Phase 1 Trial of CD33xCD3 BsAb in Pediatric Patients With Relapsed or Refractory Acute Myeloid Leukemia

BRITEPath- Phase 2

P2 Multi-center Study of SB204 Gel in the Treatment of Acne Vulgaris

International Hernia Mesh Registry

Single-Ascending Dose Study of JK07 in Subjects With HFpEF

Live Biotherapeutic Product MRx0518 and Pembrolizumab Combination Study in Solid Tumors

Evaluation of Updated Continuous Glucose Monitoring (CGM) Form Factor in Adults, Adolescents and Pediatrics

Implementing Personal Health Records to Promote Evidence-Based Cancer Screening

EMB-01 in Combination With Osimertinib in Patients With EGFR Mutant Lung Cancer