Clinical Trials in Chicago

Showing 8781-8800 of 20,493 trials

A Study Evaluating the Efficacy and Safety of the LentiGlobin® BB305 Drug Product in Participants With Transfusion-Dependent β-Thalassemia, Who do Not Have a β0/β0 Genotype

NCT02906202

This is a single-arm, multi-site, single-dose, Phase 3 study in 23 participants less than or equal to (\<=) 50 years of age with transfusion-dependent β-thalassemia (TDT), also known as β-thalassemia major, who do not have a β0 mutation at both alleles of the hemoglobin β (HBB) gene. The study will evaluate the efficacy and safety of autologous hematopoietic stem cell transplantation (HSCT) using LentiGlobin BB305 Drug Product.

Beta-Thalassemia

Genetix Biotherapeutics Inc.24 participantsStarted Aug 2016

Oakland, California, United States • Chicago, Illinois, United States • Philadelphia, Pennsylvania, United States +5 more locations

TERMINATEDPhase 12.2 miles

Study of MT-5111 in HER2-positive Solid Tumors

NCT04029922

This will be a Phase 1b, first in human, open-label, dose escalation and expansion study of MT-5111 (a recombinant fusion protein) given as monotherapy in subjects with HER2-positive solid tumors

HER2-positive Solid Cancers

Molecular Templates, Inc.50 participantsStarted Nov 2019

Phoenix, Arizona, United States • Fullerton, California, United States • Los Alamitos, California, United States +27 more locations

A Study Evaluating the Efficacy and Safety of the LentiGlobin® BB305 Drug Product in Participants With Transfusion-Dependent β-Thalassemia, Who do Not Have a β0/β0 Genotype

Study of MT-5111 in HER2-positive Solid Tumors

Find Trials by Condition in Chicago

Marimastat or No Further Therapy in Treating Women With Metastatic Breast Cancer That Is Responding or Stable Following Chemotherapy

Sunitinib Malate With or Without Gemcitabine Hydrochloride in Treating Patients With Advanced Kidney Cancer That Cannot Be Removed By Surgery

Hormone Replacement Therapy for Hot Flashes and/or Vaginal Symptoms in Postmenopausal Women Receiving Tamoxifen for Breast Cancer

Chemotherapy and Radiation Therapy in Treating Patients With Stage III or Stage IV Larynx or Oropharynx Cancer

Adjunctive Mixed Salts Amphetamine for Depressed Adults With Incomplete Response to Current Antidepressant Therapy

Combination Chemotherapy With or Without PSC 833 in Treating Patients With Relapsed or Refractory Multiple Myeloma

Identification of Genes Associated With Cancer in Patients and Siblings Who Have Cancer

Paclitaxel in Treating Patients With Metastatic or Recurrent Salivary Gland Cancer

Fluorouracil-Uracil and Leucovorin in Treating Elderly Patients With Metastatic Colorectal Cancer

A Study to Evaluate the Efficacy and Safety of CC-220 in Subjects With Active Systemic Lupus Erythematosus

Comparison of Two Combination Chemotherapy Regimens in Treating Non-small Cell Lung Cancer

Prospective Study to Evaluate a Digital Regimen for Fibromyalgia Management

(HARMONY) Study of BLU-701 in EGFR-mutant NSCLC

Examining Validity and Sensitivity of Pressure-Mediated Reflection Spectroscopy

Mobile Cardiac Telemetry and Advanced Multi-Parameter Monitoring in PatientS Wearing a Novel Device With Biometric Based Medications Changes

Treatment of Moderate to Severe Glabellar Lines

Glioma Supra Marginal Incision Trial

Treatment of Moderate to Severe Lateral Canthal Lines