Clinical Trials in Chicago

Showing 8341-8360 of 20,493 trials

Pediatric REPlAcement of the PulmonaRy ValvE in Tetralogy of Fallot -

NCT03634072

Tetralogy of Fallot (TOF) is the most common cyanotic congenital heart defect with the vast majority of survivors of corrective surgery left with some degree of right ventricular (RV) volume overload due to pulmonary regurgitation (PR) which cause RV enlargement with right heart failure, diminished biventricular function, ventricular arrhythmia, sudden death and decreased exercise performance over time. Pulmonary valve replacement (PVR) has been thought to ameliorate these complications but the timing of replacement has yet to be determined with equipoise at the moment in this decision making process. As nearly all studies in this regard are retrospective with much less data in pediatric TOF than adults, this pilot trial sets the stage to create a prospective randomized trial in the teenage years.

Tetralogy of Fallot

Children's Hospital of Philadelphia1 participantsStarted Jul 2018

Washington D.C., District of Columbia, United States • Atlanta, Georgia, United States • Chicago, Illinois, United States +3 more locations

COMPLETEDPhase 32.2 miles

Treatment of Pain Associated With Lumbosacral Radiculopathy in Adults

NCT03727100

This study will evaluate the safety and effectiveness of a new pain medication in development, clonidine micropellet. Participants will receive a single injection of either clonidine micropellet or sham injection for the treatment of low back and leg pain from sciatica.

Lumbosacral Radiculopathy

Sollis Therapeutics, Inc.207 participantsStarted Oct 2018

Mobile, Alabama, United States • Phoenix, Arizona, United States • Phoenix, Arizona, United States +30 more locations

Pediatric REPlAcement of the PulmonaRy ValvE in Tetralogy of Fallot -

Treatment of Pain Associated With Lumbosacral Radiculopathy in Adults

Find Trials by Condition in Chicago

Evaluation of Treatment Strategies for Severe CaLcIfic Coronary Arteries: Orbital Atherectomy vs. Conventional Angioplasty Technique Prior to Implantation of Drug-Eluting StEnts: The ECLIPSE Trial

Multimechanistic Treatment Over Time of Migraine Symptoms (MOVEMENT)

Study of the Effect of SZC on Serum Potassium and Serum Bicarbonate in Patients With Hyperkalemia and Metabolic Acidosis Associated With Chronic Kidney Disease

Breast Cancer Registry for Participants With Breast Cancer or Characteristics of Hereditary Breast Cancer

Bendamustine in Combination With Bortezomib and Pegylated Liposomal Doxorubicin for Multiple Myeloma

ANTHEM-HFrEF Pivotal Study

Study of the CAT RX Aspiration Catheter When Used in Patients With Large Occlusive Thrombus in Coronary Arteries

VasQ External Support for Arteriovenous Fistula

Music Therapy Video Development in Improving Communication, Emotional Distress, and Recovery in Adolescents/Young Adults Undergoing Treatment for High-Risk Cancer and Their Parents

Cooled Radiofrequency vs. Hyaluronic Acid to Manage Knee Pain

177Lu-DTPA-Omburtamab Radioimmunotherapy for Recurrent or Refractory Medulloblastoma

Safety and Tolerability Study of ISIS EIF4E Rx in Combination With Docetaxel and Prednisone (CRPC)

An Study to Evaluate the Safety and Efficacy of Copanlisib in Combination With Nivolumab in Patients With Advanced Solid Tumors

Therapeutic Use of Contrast Ultrasound in Acute Coronary Artery Disease

Rolandic Epilepsy Genomewide Association International Study

Study Of An Investigational Regimen Including FDA Approved HIV Drugs In HIV-Infected Pediatric Subjects

Use of a Tonometer to Identify Epileptogenic Lesions During Pediatric Epilepsy Surgery

Pediatric Study in Children and Adolescents With Severe Plaque Psoriasis