Clinical Trials in Chicago

Showing 5501-5520 of 20,493 trials

Conduction System Pacing With INGEVITY+

NCT06014866

The study is intended to evaluate the safety and effectiveness of the Boston Scientific INGEVITY+ cardiac pacing lead when implanted in the left bundle branch area (LBBA).

Bradycardia

Duke University1,383 participantsStarted Nov 2023

Sarasota, Florida, United States • Chicago, Illinois, United States • Indianapolis, Indiana, United States +5 more locations

Not Yet RecruitingPhase 32.2 miles

Efficacy and Safety of MSC-NTF (NurOwn) in Participants With Early Symptomatic ALS and Moderate Disease Presentation in ALS (ENDURANCE STUDY)

NCT06973629

The goal of this two-part clinical trial is: 1\) to evaluate the safety and efficacy of Debamestrocel - MSC-NTF (NurOwn) compared to placebo in participants with early symptomatic ALS and moderate disease presentation in ALS; followed by 2) further evaluation by providing NurOwn to all participants in an open label extension period. Researchers will compare NurOwn to a placebo (a look-alike substance that contains no drug) to evaluate the efficacy of NurOwn compared to placebo in the treatment of participants with ALS. Participants will: Receive NurOwn or a placebo every 8 weeks for 24 weeks. After that, every participant will receive NurOwn every 8 weeks for an additional 24 weeks. They will visit the clinic approximately every 8 weeks for checkups and tests.

Amyotrophic Lateral Sclerosis (ALS)Amyotrophic Lateral Sclerosis

Brainstorm-Cell Therapeutics200 participantsStarted Jun 2025

Phoenix, Arizona, United States • La Jolla, California, United States • Los Angeles, California, United States +12 more locations

Conduction System Pacing With INGEVITY+

Efficacy and Safety of MSC-NTF (NurOwn) in Participants With Early Symptomatic ALS and Moderate Disease Presentation in ALS (ENDURANCE STUDY)

Find Trials by Condition in Chicago

rhPSMA-73 PET-MRI Imaging for the Detection of Prostate Cancer Among Men Who Are Otherwise Candidates for Active Surveillance

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Antitumor Activity of ADCT-901 in Participants With Selected Advanced Solid Tumors

Patient-Centered Dementia Care Practice Coaching Intervention

Assessing the Accuracy of Tumor Biopsies After Chemotherapy to Determine if Patients Can Avoid Breast Surgery

Mycobacteriophage Treatment of Non-tuberculosis Mycobacteria

Rucaparib in Treating Patients With Genomic LOH High and/or Deleterious BRCA1/2 Mutation Stage IV or Recurrent Non-small Cell Lung Cancer (A Lung-MAP Treatment Trial)

A Registry for People With T-cell Lymphoma

A Study to Evaluate the Efficacy and Safety of Abiprubart in Participants With Sjögren's Disease

A Comparison of Outcomes After Anterior Cruciate Ligament (ACL) or Anterior Cruciate Ligament and Meniscus (ACL+Meniscus) Surgery Using Semiconductor Fabric Products

Safety and Efficacy Study of CFI-402411 in Subjects With Advanced Solid Malignancies

A Study of Mipasetamab Uzoptirine (ADCT-601) in Participants With Solid Tumors

A RCT Evaluating the Clinical Benefit of a Silver Dressing in the Treatment of Venous Leg Ulcers

Trial of Efficacy and Safety of NS-229 Versus Placebo in Patients With Eosinophilic Granulomatosis With Polyangiitis

Study in Patients Undergoing Debridement, Antibiotics, and Implant Retention (DAIR) for Treatment of a Periprosthetic Joint Infection (PJI) Occurring After Total Knee Arthroplasty (TKA)

An Observational Multicenter Clinical Study To Assess The Safety And Effectiveness Of The OMNI® Surgical System In Pseudophakic Eyes With Primary Open Angle Glaucoma (ORION 2.0)

FIT-ATOMIC Exercise Feasibility Trial

Efficacy, Safety and Pharmacokinetics of Rilzabrutinib in Patients With Warm Autoimmune Hemolytic Anemia (wAIHA)

NTX-001 to Repair Peripheral Nerve Transection(s)