Clinical Trials in Chicago

Showing 5361-5380 of 20,493 trials

Abraxane® With or Without Mifepristone for Advanced, Glucocorticoid Receptor-Positive, Triple-Negative Breast Cancer

NCT02788981

This is a randomized, placebo-controlled, double-blind, phase II trial of nab-paclitaxel with or without mifepristone for advanced, glucocorticoid receptor-positive, triple-negative breast cancer. A total of 64 patients will receive nab-paclitaxel. Patients will be randomly assigned to either receive placebo or to receive mifepristone daily on the day prior to and day of each dose of nab-paclitaxel. Patients will be enrolled over 12 months and followed for 12 months following completion of study. To expand and follow up on the investigators understanding of a potential pharmacokinetic (PK) interaction between nab-paclitaxel and mifepristone, investigators will perform PK studies in the first 20 patients enrolled at pre-specified "PK sites".

Breast Cancer

University of Chicago29 participantsStarted Mar 2017

Birmingham, Alabama, United States • Chicago, Illinois, United States • Evanston, Illinois, United States +2 more locations

RECRUITINGNA2.2 miles

Oxygenation in Vascular Lesions of the Colon

NCT06230731

The goal of this clinical trial is to evaluate oxygenation in the colon in people with acquired vascular abnormalities in the proximal colon.

Vascular Lesion

University of Chicago30 participantsStarted Feb 2024

Chicago, Illinois, United States

Abraxane® With or Without Mifepristone for Advanced, Glucocorticoid Receptor-Positive, Triple-Negative Breast Cancer

Oxygenation in Vascular Lesions of the Colon

Find Trials by Condition in Chicago

Study of PD1 Blockade by Pembrolizumab With Stereotactic Body Radiotherapy in Advanced Solid Tumors

Study of Orally Administered AG-120 in Subjects With Advanced Hematologic Malignancies With an IDH1 Mutation

Study of Xevinapant With Radiation and Chemotherapy for Patients With Head and Neck Cancer

Medical Access Program for Patritumab Deruxtecan

TAC T-cells for the Treatment of HER2-positive Solid Tumors

Accupressure of P6 to Reduce Nausea During Cesarean Section

Leveraging Electronic Health Record (EHR) Tools to Reduce Health Disparities for Patients With Uncontrolled Hypertension

Study of Safety and Efficacy of Pembrolizumab and Chemotherapy in Participants With Newly Diagnosed Classical Hodgkin Lymphoma (cHL) (MK-3475-C11/KEYNOTE-C11)

TRIcvalve biCAVal Valve System for Severe Tricuspid Regurgitation (TRICAV-I)

A Multi-Site Phase 3 Study of MDMA-Assisted Psychotherapy for PTSD (MAPP1)

Ipatasertib Plus Abiraterone Plus Prednisone/Prednisolone, Relative to Placebo Plus Abiraterone Plus Prednisone/Prednisolone in Adult Male Patients With Metastatic Castrate-Resistant Prostate Cancer

Validation of a Multi-gene Test for Lung Cancer Risk

Understanding the Natural History Early in the Course or Presentation of Friedreich Ataxia

JAGUAR Trial: ObJective Analysis to GaUge EVAR Outcomes Through Randomization

Promoting Shared Decision Making for Severe Aortic Stenosis

Pomalidomide in Combination With Low-dose Dexamethasone or Pomalidomide in Combination With Low-dose Dexamethasone and Daratumumab in Subjects With Relapsed or Refractory Multiple Myeloma Following Lenalidomide-based Therapy in the First or Second Line Setting

Trial of Newly Diagnosed High Grade Glioma Treated With Concurrent Radiation Therapy, Temozolomide and BMX-001

Safety and Efficacy Study of Cefepime/VNRX-5133 in Patients With Complicated Urinary Tract Infections