Clinical Trials in Chicago

Showing 5201-5220 of 20,493 trials

Nivolumab, BMS-986205, and Radiation Therapy With or Without Temozolomide in Treating Patients With Newly Diagnosed Glioblastoma

NCT04047706

This phase I trial studies the side effects of nivolumab, BMS-986205, and standard radiation therapy with or without temozolomide in treating patients with new diagnosed glioblastoma. Immunotherapy with nivolumab, may induce changes in body?s immune system and may interfere with the ability of tumor cells to grow and spread. BMS-986205 may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Radiation therapy uses high energy x-rays to kill tumor cells and shrink tumors. Drugs used in chemotherapy, such as temozolomide, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Giving nivolumab and BMS-986205 may work better compared to radiation therapy and temozolomide alone in treating patients with newly diagnosed glioblastoma.

Glioblastoma

Northwestern University18 participantsStarted Aug 2019

Chicago, Illinois, United States

COMPLETED2.2 miles

Blood and Stool Sample Collection in Subjects With a Diagnosis of Colorectal Cancer or Colorectal Lesion: Act Fast

NCT03789162

The primary objective of this study is to collect de-identified, clinically-characterized stool and whole blood specimens for use in developing and evaluating the performance of new biomarker assays for the detection of colorectal cancer (CRC).

Colorectal Cancer

Exact Sciences Corporation850 participantsStarted Dec 2018

Phoenix, Arizona, United States • Canoga Park, California, United States • Chula Vista, California, United States +42 more locations

Nivolumab, BMS-986205, and Radiation Therapy With or Without Temozolomide in Treating Patients With Newly Diagnosed Glioblastoma

Blood and Stool Sample Collection in Subjects With a Diagnosis of Colorectal Cancer or Colorectal Lesion: Act Fast

Find Trials by Condition in Chicago

Zanzalintinib in Second Line and Beyond for the Treatment of Advanced Liver Cancer

Caring Contacts Via Text Message for Suicidal Adolescents After Emergency Department Discharge

Immune Checkpoint Inhibitor Nivolumab in People With Recurrent Select Rare CNS Cancers

A Study of Daratumumab and Dose-Adjusted EPOCH in Plasmablastic Lymphoma

Adolescent Master Protocol for Participants 18 Years of Age or Older - Lite

24 Weeks Double-blind Randomized Placebo-controlled Trial to Evaluate Efficacy, PK, Safety of LOU064 in Adolescents (12 - <18) With CSU and Inadequate Response to H1-antihistamine Followed by Optional 3 Years Open-label Extension and an Optional 3 Years Safety Long-term Treatment-free Follow-up

Safety and Efficacy Study of 10XB-101 in Adults With Bilateral Flank Adiposity

A Depression and Opioid Pragmatic Trial in Pharmacogenetics (Depression Trial)

Distal Radius Interventions for Fracture Treatment

Beacon Sensors and Telerehabilitation for Low Vision

BIG Study (Brain, Immune, and Gut Health Evaluation of Infants/Young Children Fed Infant Formula, and Later Supplemental Toddler Nutrition, With 5 Specific HMOs)

LTFU for All Cell and Gene Therapy Studies

Intramyocardial Injection of Autologous UCB-MNC During Fontan Surgery for SRV Dependent CHD

Safety, Tolerability & Potential Anti-cancer Activity of Increasing Doses of AZD5363 in Different Treatment Schedules

Personalized AZithromycin/metronidAZole Therapy in Pediatric Crohn's Disease (CD)

Glaucoma Drainage Device and Endothelial Cell Loss Compare Trial

FS120 Phase 1/1b Study in Patients With Advanced Malignancies

Benchmark Evidence Led by Latin America: Trial of Intracranial Pressure - Pediatrics