Clinical Trials in Chicago

Showing 5141-5160 of 20,493 trials

Time-restricted Eating Versus Daily Continuous Calorie Restriction on Body Weight and Colorectal Cancer Risk Markers

NCT05114798

Approximately 42% of American adults are obese, and this condition is strongly related to the development of colorectal cancer. Innovative lifestyle strategies to treat obesity and reduce colorectal cancer risk are critically needed. This research will demonstrate that time-restricted eating, a type of intermittent fasting, is an effective therapy to help obese individuals reduce and control their body weight and prevent the development of colorectal cancer.

Time Restricted EatingObesityWeight Loss+1 more

University of Illinois at Chicago255 participantsStarted May 2022

Chicago, Illinois, United States

Active Not RecruitingPhase 12.2 miles

Testing the Addition of an Anti-cancer Drug, Adavosertib, to Radiation Therapy for Patients With Incurable Esophageal and Gastroesophageal Junction Cancers

NCT04460937

This phase I trial investigates the side effects and best dose of adavosertib and how well it works when given in combination with radiation therapy in treating patients with esophageal or gastroesophageal junction cancer for which no treatment is currently available (incurable). Adavosertib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Radiation therapy uses high energy x-rays to kill tumor cells and shrink tumors. Giving adavosertib together with radiation therapy kill more tumor cells than radiation therapy alone in treating patients with esophageal and gastroesophageal junction cancer.

Clinical Stage III Esophageal Adenocarcinoma AJCC v8Clinical Stage III Esophageal Squamous Cell Carcinoma AJCC v8Clinical Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8+56 more

National Cancer Institute (NCI)4 participantsStarted Apr 2021

Duarte, California, United States • Chicago, Illinois, United States • Lexington, Kentucky, United States +4 more locations

Time-restricted Eating Versus Daily Continuous Calorie Restriction on Body Weight and Colorectal Cancer Risk Markers

Testing the Addition of an Anti-cancer Drug, Adavosertib, to Radiation Therapy for Patients With Incurable Esophageal and Gastroesophageal Junction Cancers

Find Trials by Condition in Chicago

A Study to Compare the Efficacy and Safety of SCENESSE and Narrow-Band Ultraviolet (NB-UVB) Light Versus NB-UVB Light Alone in Patients With Vitiligo

Basic Experimental Study of Hippocampal Memory Functions

Novel Visual Education Tool to Improve Recognition and Reporting of Postpartum Urgent Maternal Warning Signs

Walking Balance Training Post-Stroke

CHIO3 Trial: CHemotherapy Combined With Immune Checkpoint Inhibitor for Operable Stage IIIA/B Non-Small Cell Lung Cancer

Efficacy of Oral Azacitidine Plus Best Supportive Care as Maintenance Therapy in Subjects With Acute Myeloid Leukemia (AML) in Complete Remission

A Ph2b to Evaluate Clinical Efficacy and Safety of Tildacerfont in Adult CAH

A Study of the Bruton's Tyrosine Kinase Inhibitor Ibrutinib Given in Combination With Bendamustine and Rituximab in Patients With Newly Diagnosed Mantle Cell Lymphoma

ROSE-Longitudinal Assessment With Neuroimaging

Prospective Multicenter Research on Donor and Recipient Management Strategies to Improve Lung Transplant Outcomes

RNS System NAUTILUS Study

Efficacy and Safety of Lorundrostat in Addition to Sodium-Glucose Cotransporter-2 Inhibitors (SGLT2i) in Subjects With Hypertension and Chronic Kidney Disease (CKD) With Albuminuria

Intramyocardial Injection of Autologous Umbilical Cord Blood Derived Mononuclear Cells During Surgical Repair of Hypoplastic Left Heart Syndrome

STRIDE Study - A Study in Subjects With LOPD Who Are Currently Being Treated With ERT

Adaptive DBS Algorithm for Personalized Therapy in Parkinson's Disease

GWICTIC: NAC Mechanistic Study in Gulf War Veterans

A Study of GlcNAc on Tear Production in NGLY1-CDDG

Stage II/III Colorectal Cancer Recurrence