Clinical Trials in Chicago

Showing 4841-4860 of 20,493 trials

Haplo T-Cell Depleted Transplantation in High-Risk Sickle Cell Disease

NCT01461837

This study is being done to determine the safety and outcome (long-term control) of a high-dose chemotherapy regimen followed by an infusion of CD34 selected (immune cells) stem cells from a partially matched adult family member donor, called haploidentical stem cell transplantation, in high-risk sickle cell disease patients. Funding Source - FDA OOPD

Sickle Cell Disease

New York Medical College21 participantsStarted Jan 2012

Los Angeles, California, United States • Oakland, California, United States • Chicago, Illinois, United States +3 more locations

Active Not RecruitingPhase 32.2 miles

To Evaluate the Efficacy and Safety of Pegozafermin in Subjects With Severe Hypertriglyceridemia

NCT05852431

To determine the effect of Pegozafermin on fasting serum triglyceride levels in subjects with Severe Hypertriglyceridemia (TG ≥500 to ≤2000 mg/dL) after 26 weeks of treatment.

Severe Hypertriglyceridemia

89bio, Inc.360 participantsStarted Jun 2023

Chandler, Arizona, United States • Peoria, Arizona, United States • Tucson, Arizona, United States +174 more locations

Haplo T-Cell Depleted Transplantation in High-Risk Sickle Cell Disease

To Evaluate the Efficacy and Safety of Pegozafermin in Subjects With Severe Hypertriglyceridemia

Find Trials by Condition in Chicago

Evaluation of Talazoparib, a PARP Inhibitor, in Patients With Somatic BRCA Mutant Metastatic Breast Cancer: Genotyping Based Clinical Trial

Phase 1, First-in-human, Dose-finding and Expansion Study to Evaluate XmAb®808 in Combination With Pembrolizumab in Advanced Solid Tumors

LimiFlex Clinical Trial for the Treatment of Degenerative Spondylolisthesis With Spinal Stenosis

Hemodynamic-GUIDEd Management of Heart Failure

Prophylactic Minimally Invasive Surfactant Evaluation

DNA Evaluation of Fragments for Early Interception - Lung Cancer Training Study (DELFI-L101 Study)

EBV-specific Cytotoxic T-lymphocytes (CTLs) for Refractory EBV Infection

The Imperative Trial: Treatment of Acute Ischemic Stroke With the Zoom Reperfusion System

LOGiC - Lapatinib Optimization Study in ErbB2 (HER2) Positive Gastric Cancer: A Phase III Global, Blinded Study Designed to Evaluate Clinical Endpoints and Safety of Chemotherapy Plus Lapatinib

Hepcidin Mimetic in Patients With Polycythemia Vera (REVIVE)

A Phase 1 Clinical Study of NXP800 in Subjects With Advanced Cancers and Expansion in Subjects With Ovarian Cancer

Safety and Efficacy Study of CC-486 With MK-3475 to Treat Locally Advanced or Metastatic Non-small Cell Lung Cancer

Fitusiran Prophylaxis in Male Pediatric Subjects Aged 1 to Less Than 12 Years With Hemophilia A or B

Phase II Decitabine (DAC) Versus Azacitidine (AZA) in Myelodysplastic Syndrome (MDS)

Safety and Efficacy of GSK Neisseria Gonorrhoeae GMMA (NgG) Investigational Vaccine When Administered to Healthy Adults 18 to 50 Years of Age.

A Study of Trastuzumab Emtansine in Combination With Atezolizumab or Placebo as a Treatment for Participants With Human Epidermal Growth Factor 2 (HER2)-Positive and Programmed Death-ligand 1 (PD-L1)-Positive Locally Advanced (LABC) or Metastatic Breast Cancer (MBC)

Intranasal Oxytocin for the Treatment of Alcohol Use Disorder

Conventional Endoscopic Techniques Versus EndoRotor® System for Necrosectomy of Walled of Necrosis