Clinical Trials in Chicago

Showing 4741-4760 of 20,493 trials

Movement Amplification Gait Training to Enhance Walking Balance Post-Stroke

NCT06400186

Stroke is a leading cause of disability in the United States, affecting approximately 795,000 people annually. The Veteran's Health Administration provides over 60,000 outpatient visits for stroke-related care annually at a cost of over $250 million. Among ambulatory people with chronic stroke (PwCS), impaired balance is a common health concern that substantially limits mobility (those with the worst balance walk the least). This project will explore adaptive strategies employed by PwCS in balance challenging environments and if a novel gait training intervention using a robotic device to amplify a person's self-generated movements can improve walking balance. The development of effective interventions to increase walking balance among PwCS will positively impact Veterans' health, quality of life, and ability to participate in walking activities.

Chronic Hemiparetic Stroke

VA Office of Research and Development30 participantsStarted Aug 2024

Chicago, Illinois, United States • Hines, Illinois, United States

RECRUITINGPhase 22.2 miles

Combination Therapies With Adagrasib in Patients With Advanced NSCLC With KRAS G12C Mutation

NCT05609578

Study CA239-0010 is an open-label, Phase 2 clinical trial evaluating the clinical efficacy of adagrasib in combination with pembrolizumab and chemotherapy in the first-line setting for patients with advanced NSCLC with TPS ≥ 1%, TPS \<50% and KRAS G12C mutation

Advanced NSCLCMetastatic Lung Cancer

Mirati Therapeutics Inc.90 participantsStarted Nov 2022

Anchorage, Alaska, United States • Glendale, Arizona, United States • Phoenix, Arizona, United States +163 more locations

Movement Amplification Gait Training to Enhance Walking Balance Post-Stroke

Combination Therapies With Adagrasib in Patients With Advanced NSCLC With KRAS G12C Mutation

Find Trials by Condition in Chicago

Main Study: A Study to Evaluate the Effectiveness and Safety of GAL1906 for Correction of Wrinkles in the décolletage Area Sub-study: A Follow-up Study to Evaluate the Analysis of Mammograms Following Treatment for Correction of Wrinkles in Décolletage Area in the Investigational Study 43USRV1906

Study of Zanzalintinib (XL092) + Pembrolizumab vs Pembrolizumab in Subjects With PD-L1 Positive Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma

Aging and Mixed Perturbation Training to Reduce Falls in Locomotion

Piloting a Culturally Adapted Suicide Prevention for Black Students in Chicago

Lupus Landmark Study: A Prospective Registry and Biorepository

Veliparib With or Without Carboplatin in Treating Patients With Stage III or IV Breast Cancer

A Study to Investigate the Efficacy and Safety of Verekitug (UPB-101) in Participants With Chronic Rhinosinusitis With Nasal Polyps

A Multi-Center, Prospective, Observational Study of Patients Being Treated With ORGOVYX

ALPN-101 (Acazicolcept) in Systemic Lupus Erythematosus

Study of EYP-1901 in Patients With Nonproliferative Diabetic Retinopathy (NPDR)

Minimal Residual Disease Testing for the Early Detection of Cancer Recurrence in Resectable Stage II-IV Colorectal Cancer Patients

Severe Asthma Research Program

A Study of ADRX-0706 in Select Advanced Solid Tumors

Efficacy and Safety of Pembrolizumab (MK-3475) With Lenvatinib (E7080/MK-7902) vs. Docetaxel in Participants With Metastatic Non-Small Cell Lung Cancer (NSCLC) and Progressive Disease (PD) After Platinum Doublet Chemotherapy and Immunotherapy (MK-7902-008/E7080-G000-316/LEAP-008)

Actis Total Hip System 2 Year Follow-up

Blinatumomab and Nivolumab With or Without Ipilimumab in Treating Patients With Poor-Risk Relapsed or Refractory CD19+ Precursor B-Lymphoblastic Leukemia

Study of Safety and Tolerability of BCA101 Monotherapy and in Combination Therapy in Patients With EGFR-driven Advanced Solid Tumors

A Study of XPro1595 in Patients With Early Alzheimer's Disease With Biomarkers of Inflammation