Clinical Trials in Chicago

Showing 441-460 of 17,609 trials

Autologous Bone Marrow Aspirate Concentrate in Patients Undergoing Meniscectomy

NCT02582489

The proposed research study aims to evaluate the effects of autologous bone marrow aspirate concentrate (BMAC) on the development and progression of osteoarthritis (OA) in patients undergoing meniscectomy. This prospective, randomized, double-blind clinical trial will compare patient-reported outcomes, specifically IKDC scores between patients who receive BMAC post-meniscectomy and those who receive a saline control injection. The study will also compare physical examination, MRI, radiographs, and synovial fluid analysis. Our hypothesis is that those who receive the autologous BMAC injection after the procedure will have better outcomes than those who do not.

Osteoarthritis Post-meniscectomy

Rush University Medical Center100 participantsStarted Dec 2017

Chicago, Illinois, United States

RECRUITINGPhase 22.2 miles

A Trial to Investigate the Safety and Efficacy of Intra-articular 4P004 Injection in Subjects With Knee Synovitis and Osteoarthritis

NCT07225829

This phase 2a trial is an international, multicenter, randomized, double-blind, placebo-controlled trial to investigate the efficacy and safety of one single intra-articular (IA) injection of 4P004 or placebo in: * patients between 40 and 80 years of age, * with synovitis and grade 2 to 4 osteoarthritis (OA) of the knee according to Kellgren and Lawrence (KL) classification.

Knee OsteoarthritisSynovitis of Knee

4Moving Biotech129 participantsStarted Jun 2025

Tucson, Arizona, United States • Chicago, Illinois, United States • Burlington, Massachusetts, United States +19 more locations

Autologous Bone Marrow Aspirate Concentrate in Patients Undergoing Meniscectomy

A Trial to Investigate the Safety and Efficacy of Intra-articular 4P004 Injection in Subjects With Knee Synovitis and Osteoarthritis

Find Trials by Condition in Chicago

N2004-04: Fenretinide LXS in Treating Patients With Recurrent, Refractory, or Persistent Neuroblastoma

Docetaxel to Androgen Receptor Pathway Inhibitors in Patients With Metastatic Castration Sensitive Prostate Cancer and Suboptimal PSA Response

Clinical Decision Support Tool in PARDS Pilot Study

Targeted Therapy Directed by Genetic Testing in Treating Pediatric Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphomas, or Histiocytic Disorders (The Pediatric MATCH Screening Trial)

Savolitinib vs. Sunitinib in MET-driven PRCC.

Regional Radiotherapy in Biomarker Low-Risk Node Positive and T3N0 Breast Cancer

Coronary Computed Tomography Study to Assess the Effect of Inclisiran in Addition to Maximally Tolerated Statin Therapy on Atherosclerotic Plaque Progression in Participants With a Diagnosis of Non-obstructive Coronary Artery Disease Without Previous Cardiovascular Events

SIMPLAAFY Clinical Trial

An Expanded Access Program of Cretostimogene Grenadenorepvec for Treatment of NMIBC for Patients Unresponsive to BCG

Medrol Dosepak for Outpatient Total Knee Arthroplasty

A Study of the Safety and Effectiveness of the Mentor Larger Size MemoryGel Ultra High Profile Breast Implants in Subjects Who Are Undergoing Primary Breast Reconstruction or Revision Reconstruction

A Study to Assess BMS-986458 Alone and in Combination With Anti-lymphoma Agents in Relapsed/Refractory Non-Hodgkin Lymphomas

Retinoblastoma Phase II Expanded Access Clinical Trial

A Study of ZW251 in Participants With Advanced Solid Tumors

NP-G2-044 as Monotherapy and Combination Therapy in Patients With Advanced or Metastatic Solid Tumor Malignancies

Evaluation of VX-828 in Healthy Participants and in Participants With Cystic Fibrosis

Study of Plozasiran (ARO-APOC3) in Adults With Mixed Dyslipidemia

Study of Voicing My CHOiCES as a Tool for Advanced Care Planning in Young Adults With Cancer