Clinical Trials in Chicago

Showing 3601-3620 of 17,609 trials

Metabolic Mechanisms Induced by Enteral DHA and ARA Supplementation in Preterm Infants

NCT05380401

A comprehensive analysis of the impact of exogenous enteral DHA and ARA supplementation on lipid metabolism including the production of downstream derived mediators and how this impacts important biological pathways such as metabolism, inflammation, and organogenic factors.

Premature

The University of Texas Health Science Center at San Antonio328 participantsStarted Mar 2023

Los Angeles, California, United States • New Haven, Connecticut, United States • Chicago, Illinois, United States +4 more locations

RECRUITINGPhase 22.2 miles

Brentuximab Vedotin and Nivolumab for the Treatment of Patients With Relapsed/Refractory Classical Hodgkin Lymphoma

NCT04561206

This phase II trial investigates how well brentuximab vedotin and nivolumab work in treating patients with classical Hodgkin lymphoma that has come back after initial treatment (relapsed) or has not responded to initial treatment (refractory). Brentuximab vedotin is a monoclonal antibody, brentuximab, linked to a toxic agent called vedotin. Brentuximab attaches to CD30 positive cancer cells in a targeted way and delivers vedotin to kill them. Nivolumab is an antibody that enhances the immune system to better fight Hodgkin lymphoma cells. Giving brentuximab vedotin and nivolumab may be able to defer stem cell transplant treatment and spare the considerable cost and toxicity on transplantation.

Relapsed Classic Hodgkin Lymphoma

City of Hope Medical Center31 participantsStarted Nov 2021

Duarte, California, United States • Chicago, Illinois, United States • Boston, Massachusetts, United States +2 more locations

Metabolic Mechanisms Induced by Enteral DHA and ARA Supplementation in Preterm Infants

Brentuximab Vedotin and Nivolumab for the Treatment of Patients With Relapsed/Refractory Classical Hodgkin Lymphoma

Find Trials by Condition in Chicago

A Study Evaluating the Long-term Safety and Efficacy of VX-445 Combination Therapy

Study to Evaluate Safety and Efficacy of VX-661 in Combination With Ivacaftor in Subjects With Cystic Fibrosis, Homozygous for the F508del-CFTR Mutation With an Open-Label Expansion

Single-Sided Deafness and Asymmetric Hearing Loss

TArgeting Type 1 Diabetes Using POLyamines (TADPOL)

CAB-AXL-ADC Safety and Efficacy Study in Adult and Adolescent Patients With Sarcoma

Stereotactic Body Radiotherapy (SBRT) for Early Treatment of Oligometastatic Adenoid Cystic Carcinoma: The SOLAR Trial

Phase 2 Safety and Efficacy Evaluation of AL8326 in ≥2nd Line SCLC

Computerized Registry of Patients With Venous Thromboembolism (RIETE)

A Study to Evaluate the Efficacy and Safety of BLI5100 in Patients With Erosive Esophagitis

NTX-301 in MDS/AML

Treatment of Obstructive Sleep Apnea With Personalized Surgery in Children With Small Tonsils

Evaluate the Safety, Efficacy, and Pharmacokinetics of CRN04894 in Participants With Congenital Adrenal Hyperplasia (TouCAHn)

Effect of Inhaled Technosphere Insulin vs RAA Insulin on Exercise-Induced Hypoglycemia in Adults With T1D Using Automated Insulin Delivery

Comparing Hypothermic Temperatures During Hemiarch Surgery

An Extension Study to Evaluate Safety and Efficacy in Participants Treated With CRN04894

Study of Lenacapavir and Emtricitabine/Tenofovir Disoproxil Fumarate (F/TDF) in Prevention of HIV in Cisgender Women in the United States (HPTN 102)

Natural History and Biospecimen Acquisition for Children and Adults With Rare Solid Tumors

Phase1/2a Study for IPG7236 in Patients With Advanced Solid Tumors