Clinical Trials in Chicago

Showing 3301-3320 of 17,609 trials

Safety, Tolerability, and Exploratory Efficacy Study of Intrathecally Administered Gene Therapy AMT-162 in Adult Participants With SOD1 Amyotrophic Lateral Sclerosis (SOD1-ALS)

NCT06100276

This is the study of AMT-162 in Participants with SOD1-ALS and is designed to evaluate the safety, tolerability, and exploratory efficacy of intrathecally administered gene therapy AMT-162. AMT-162-001 is a Phase 1/2, multi-center, single ascending dose study.

Amyotrophic Lateral Sclerosis

UniQure Biopharma B.V.20 participantsStarted Aug 2024

Phoenix, Arizona, United States • Irvine, California, United States • San Francisco, California, United States +9 more locations

COMPLETEDPhase 12.2 miles

Vincristine Sulfate Liposome Injection (Marqibo®) in Combination With UK ALL R3 Induction Chemotherapy

NCT02879643

This is a pilot study utilizing Marqibo® (vincristine sulfate liposome injection) combined with dexamethasone, mitoxantrone and asparaginase (UK ALL R3) for relapsed acute lymphoblastic leukemia (ALL).

ALL, ChildhoodLymphoblastic Leukemia, Acute, ChildhoodLymphoblastic Leukemia, Acute

Therapeutic Advances in Childhood Leukemia Consortium29 participantsStarted Jan 2017

Los Angeles, California, United States • Orange, California, United States • San Francisco, California, United States +32 more locations

Safety, Tolerability, and Exploratory Efficacy Study of Intrathecally Administered Gene Therapy AMT-162 in Adult Participants With SOD1 Amyotrophic Lateral Sclerosis (SOD1-ALS)

Vincristine Sulfate Liposome Injection (Marqibo®) in Combination With UK ALL R3 Induction Chemotherapy

Find Trials by Condition in Chicago

Extension Study to Evaluate Safety and Efficacy of CTP-543 in Adults With Alopecia Areata

Safety and Proof-of-Concept (POC) Study With AMT-130 in Adults With Early Manifest Huntington's Disease

Study of RP-3500, Camonsertib, in Advanced Solid Tumors

Nonhealing Diabetic Foot Ulcers Treated With Standard of Care (SOC) Alone or Standard of Care and Amnion-Intermediate-Chorion (AIC)

Relugolix and Enzalutamide in Combination With Radiation Therapy for the Treatment of Very High Risk Prostate Cancer, OPTIMAL Trial

Trial of Indication-Based Transfusion of Red Blood Cells in ECMO

To Evaluate Efficacy and Safety of Serplulimab + Chemotherapy (Carboplatin- Etoposide) in US Patients With ES-SCLC

Extended-Release Naltrexone and Monthly Extended-Release Buprenorphine for Cocaine Use Disorder (CURB-2)

Tomivosertib in Relapsed or Refractory Acute Myeloid Leukemia (AML)

Azacitidine Combined With Pembrolizumab and Epacadostat in Subjects With Advanced Solid Tumors (ECHO-206)

GRAVITAS-119: Itacitinib in Combination With Calcineurin Inhibitor-Based Interventions for the Prophylaxis of Graft-Versus Host Disease

Medtronic Transcatheter Aortic Valve Replacement (TAVR) Low Risk Bicuspid Study

Study of Daxdilimab (HZN-7734) in Participants With Moderate-to-Severe Primary Discoid Lupus Erythematosus

Open-Label Safety and Tolerability Study of INCB057643 in Subjects With Advanced Malignancies

A Study of ZW171 in Participants With Advanced or Metastatic Mesothelin-expressing Cancers

Ultrasound-Guided Percutaneous Cryoneurolysis to Treat Postoperative Pain After Mastectomy

Artacent Amniotic Tissue for Treatment of Chronic Lower Extremity Diabetic Ulcers.

Hearing Impairment, Strategies and Outcomes in VA Emergency Departments