Clinical Trials in Chicago

Showing 2401-2420 of 17,609 trials

A Study Evaluating B Cell Levels In Infants Of Lactating Women With CIS Or MS Receiving Ocrelizumab

NCT04998851

This study will evaluate the pharmacokinetics of ocrelizumab in the breastmilk of lactating women with clinically isolated syndrome (CIS) or multiple sclerosis (MS) \[in line with the locally approved indications\] treated with ocrelizumab, by assessing the concentration of ocrelizumab in mature breastmilk, as well as the corresponding exposure and pharmacodynamic effects (blood B cell levels) in the infants.

Multiple SclerosisClinically Isolated Syndrome

Hoffmann-La Roche26 participantsStarted Sep 2021

San Francisco, California, United States • Aurora, Colorado, United States • Chicago, Illinois, United States +5 more locations

RECRUITINGPhase 42.2 miles

Abemaciclib Dose Escalation to Maintain Intensity (ADE-MI)

NCT06169371

This is a post-marketing single arm, phase IV trial in which patients with high-risk early-stage HR+HER2- breast cancer will receive adjuvant abemaciclib in combination with endocrine therapy (ET) After study intervention, participants will remain on combination abemaciclib + ET at the discretion of their treating providers

Breast Cancer

University of Illinois at Chicago50 participantsStarted Dec 2023

Chicago, Illinois, United States • Iowa City, Iowa, United States • Columbus, Ohio, United States

A Study Evaluating B Cell Levels In Infants Of Lactating Women With CIS Or MS Receiving Ocrelizumab

Abemaciclib Dose Escalation to Maintain Intensity (ADE-MI)

Find Trials by Condition in Chicago

Telehealth Education Leveraging Electronic Transitions Of Care for COPD Patients

SCI Acute Intermittent Hypoxia and Non-Invasive Spinal Stimulation Combined With Gait Training

Safety and Efficacy of Efavaleukin Alfa in Participants With Moderately to Severely Active Ulcerative Colitis

FORAGER-1: A Study of LOXO-435 (LY3866288) in Participants With Cancer With a Change in a Gene Called FGFR3

Proact: A Study of REACT in Subjects With Type 2 Diabetes Mellitus and Chronic Kidney Disease

A Pivotal Safety and Efficacy Study of OCS-01 Eye Drops in Participants With Diabetic Macular Edema (DIAMOND 2)

Algorithm Using LINQ Sensors for Evaluation And Treatment of Heart Failure

A Study of the Safety and Tolerability of ASP7317 in Senior Adults Who Are Losing Their Clear, Sharp Central Vision Due to Geographic Atrophy Secondary to Dry Age-related Macular Degeneration

A Safety, Tolerability and Pharmacokinetics Study of VRDN-003 in Participants With Thyroid Eye Disease (TED)

A Study of MGD024 in Patients With Relapsed or Refractory Hematologic Malignancies

Liver Cirrhosis Network Cohort Study

Study of DECOY20 With or Without Tislelizumab in Patients With Advanced Solid Tumors

A Single Arm Study Evaluating the Efficacy, Safety and Tolerability of Ofatumumab in Patients With Relapsing Multiple Sclerosis

Single Arm, Open Label Trial With Iptacopan Treatment for 24 Weeks, in Patients on Stable Regimen of Anti-C5 Who Switch to Iptacopan.

Risk-Adapted Therapy for Young Children With Embryonal Brain Tumors, Choroid Plexus Carcinoma, High Grade Glioma or Ependymoma

ALRN-6924 in Patients With Advanced Solid Tumors or Lymphomas

PHE885 CAR-T Therapy in Adult Participants With Relapsed and Refractory Multiple Myeloma

Nuwiq Dosing and Outcomes In the ManagEment of Women/Girls With Haemophilia A Needing FVIII Treatment for Surgery