Clinical Trials in Chicago

Showing 2321-2340 of 17,609 trials

Interventional Study of Vosoritide for the Treatment of Children With Hypochondroplasia

NCT06455059

The intent and design of this Phase 3 study is to assess vosoritide as a therapeutic option for the treatment of children with hypochondroplasia (HCH).

Hypochondroplasia

BioMarin Pharmaceutical80 participantsStarted Jun 2024

Wilmington, Delaware, United States • Washington D.C., District of Columbia, United States • Chicago, Illinois, United States +20 more locations

RECRUITINGPhase 32.2 miles

Study of Sacituzumab Govitecan-hziy and Pembrolizumab Versus Treatment of Physician's Choice in Patients With Triple Negative Breast Cancer Who Have Residual Invasive Disease After Surgery and Neoadjuvant Therapy (ASCENT-05/AFT-65 OptimICE-RD/GBG 119/NSABP B-63)

NCT05633654

The goal of this study is to find out if the experimental product, sacituzumab govitecan-hziy (SG) in combination with pembrolizumab given after surgery, is effective and safe compared to the treatment of physician's choice (TPC) which includes either pembrolizumab or pembrolizumab plus capecitabine in participants with triple negative breast cancer that still remains after surgery and pre-surgical treatment.

Triple Negative Breast Cancer

Gilead Sciences1,514 participantsStarted Dec 2022

Birmingham, Alabama, United States • Huntsville, Alabama, United States • Glendale, Arizona, United States +285 more locations

Interventional Study of Vosoritide for the Treatment of Children With Hypochondroplasia

Study of Sacituzumab Govitecan-hziy and Pembrolizumab Versus Treatment of Physician's Choice in Patients With Triple Negative Breast Cancer Who Have Residual Invasive Disease After Surgery and Neoadjuvant Therapy (ASCENT-05/AFT-65 OptimICE-RD/GBG 119/NSABP B-63)

Find Trials by Condition in Chicago

Unresectable Stage IIIA/IIIB Non-small Cell Lung Cancer (NSCLC)

SGLT2 Inhibitors as a Novel Treatment for Pediatric Non-Alcoholic Fatty Liver Disease

Expanded Access Protocol for Boys With Duchenne Muscular Dystrophy

Efficacy and Safety of Erenumab in Pediatric Subjects With Chronic Migraine

A Phase I/II Study of Nivolumab, Ipilimumab and Plinabulin in Patients With Recurrent Small Cell Lung Cancer

EXActDNA-003 / NSABP B-64: Study of Molecular Residual Disease Detection in Breast Cancer (MRD)

A Phase III Study to Assess the Effect of AZD0780 on LDL-C in Patients With Clinical ASCVD or at Risk for a First ASCVD Event

A Study of Amivantamab in Combination With Lazertinib, or Amivantamab in Combination With Platinum-Based Chemotherapy, for Common Epidermal Growth Factor Receptor (EGFR)-Mutated Locally Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC)

Evaluation of the Efficacy and Safety of Magnetic Resonance Angiography (MRA) Using Gadopiclenol Compared to Gadoterate Meglumine in the Assessment of Steno-occlusive Disease in Adult Patients With Suspected Vascular Disease

Efficacy and Safety of Tildrakizumab Compared to Placebo in Subjects With Active Psoriatic Arthritis I (INSPIRE 1)

A Study of Tiragolumab in Combination With Atezolizumab in Chemotherapy-Naïve Patients With Locally Advanced or Metastatic Non-Small Cell Lung Cancer

Anticoagulation for New-Onset Post-Operative Atrial Fibrillation After CABG

Study of the RNR Inhibitor BBI-825 in Subjects With Tumors With Resistance Gene Amplifications

Study of Orally Administered MOMA-341 in Participants With Advanced or Metastatic Solid Tumors

CLN-049 in Patients With Relapsed/Refractory Acute Myeloid Leukemia (AML) or Myelodysplastic Syndrome (MDS)

Statins for the Treatment of NASH

A Phase IIb Study to Evaluate the Safety of Zibotentan/Dapagliflozin in Participants With Cirrhosis-ZEAL-UNLOCK

Study to Assess Safety, Tolerability and Activity of DSB2455 in Participants With Advanced Malignancies