Clinical Trials in California

Showing 681-700 of 9,745 trials

RECRUITING63 miles

Objective Assessment of Intraocular Lens Tilt and Decentration

NCT07324200

Prospective, multi-center, non-interventional, open label, randomized clinical study.

Tilt and Decentration

Johnson & Johnson Surgical Vision, Inc.80 participantsStarted Mar 2026

Bakersfield, California, United States • Sioux City, Iowa, United States

RECRUITINGPhase 3159 miles

Phase III, Open-label, Study of First-line Dato-DXd in Combination With Rilvegostomig for Advanced Non-squamous NSCLC With High PD-L1 Expression (TC ≥ 50%) and Without Actionable Genomic Alterations

NCT06357533

The purpose of this study is to evaluate efficacy and safety of Dato-DXd in combination with rilvegostomig or rilvegostomig monotherapy compared with pembrolizumab monotherapy as a first line therapy in participants with locally advanced or metastatic non-squamous NSCLC with high PD-L1 expression (TC ≥ 50%) and without actionable genomic alterations.

Non-Small Cell Lung Cancer

AstraZeneca675 participantsStarted Apr 2024

Anchorage, Alaska, United States • Tucson, Arizona, United States • Little Rock, Arkansas, United States +278 more locations

Objective Assessment of Intraocular Lens Tilt and Decentration

Phase III, Open-label, Study of First-line Dato-DXd in Combination With Rilvegostomig for Advanced Non-squamous NSCLC With High PD-L1 Expression (TC ≥ 50%) and Without Actionable Genomic Alterations

Find Trials by Condition in California

Extension Study of Oral PHA-022121 for Acute Treatment of Angioedema Attacks in Patients With Hereditary Angioedema

Study of Patritumab Deruxtecan in Participants With Gastrointestinal Cancers (MK-1022-011) (HERTHENA-PanTumor02)

A Real-World Study to Gain Clinical Insights Into Roche Ophthalmology Products

A Study of CBX-250 in Participants With Relapsed or Refractory Myeloid Leukemias

An International Observational Study of Adults With Acute Infection

(Neo)Adjuvant IDE196 (Darovasertib) in Patients With Localized Ocular Melanoma

I-SPY COVID-19 TRIAL: An Adaptive Platform Trial for Critically Ill Patients

Study to Assess the Safety and Tolerability of Tafasitamab in Adult Participants With Primary Autoimmune Blood Cell Disorders

A Study to Evaluate the Efficacy and Safety of GDC-8264 in Preventing Cardiac Surgery-Associated Acute Kidney Injury (AKI) and Major Adverse Kidney Events (MAKE)

Soquelitinib vs Standard of Care in Participants With Relapsed/Refractory Peripheral T-cell Lymphoma Not Otherwise Specified, Follicular Helper T-cell Lymphomas, or Systemic Anaplastic Large-cell Lymphoma

KEYMAKER-U01 Umbrella Master Study: Studies of Investigational Agents With Either Pembrolizumab (MK-3475) Alone or With Pembrolizumab PLUS Chemotherapy in Participants With Non-small Cell Lung Cancer (NSCLC) (MK-3475-U01/KEYMAKER-U01)

Safety of RSV Preventive Monoclonal Antibody

A Safety and Immunogenicity Trial of Boost-2867 Vaccine, Via Intranasal and Intramuscular Routes

A Clinical Study of KTX-2001 in Subjects With Metastatic Castration-Resistant Prostate Cancer (STRIKE-001)

Premedication to Reduce Amivantamab Associated Infusion Related Reactions

Multicenter Clinical Trial of a Phakic Implantable Collamer® Lens (ICL)

A Study of JNJ-90301900 in Combination With Chemoradiation Followed by Consolidation Immunotherapy for Non-Small Cell Lung Cancer (NSCLC)

Proof-of-concept of a Behavioral Intervention to Improve the Cardiovascular Health of People Living With HIV