Clinical Trials in California

Showing 6461-6480 of 11,359 trials

Open-Label Study of OTO-201 for Treatment of AOMT

NCT02408796

This is a 1-month, prospective, multicenter, open-label study in pediatric subjects with either unilateral or bilateral acute otitis media with tympanostomy tubes (AOMT). Eligible subjects will receive a single dose of 6 mg OTO-201 to the affected ear(s). The study is designed to characterize safety, procedural factors and clinical effect of OTO-201 administered in subjects with AOMT.

Acute Otitis MediaAOMT

Otonomy, Inc.39 participantsStarted Mar 2015

Fresno, California, United States • Fort Lauderdale, Florida, United States • Charlotte, North Carolina, United States +2 more locations

COMPLETEDPhase 344 miles

Pentosan Polysulfate in Treating Patients With Gastrointestinal Disturbance Caused by Radiation Therapy

NCT00003825

RATIONALE: Pentosan polysulfate may be effective in treating side effects of radiation therapy to the abdomen or pelvis. It is not yet known whether pentosan polysulfate is more effective than no further therapy for treating gastrointestinal disturbance caused by previous radiation therapy. PURPOSE: Randomized phase III trial to determine the effectiveness of pentosan polysulfate in treating patients who have inflammation of the rectum, diarrhea, or blood in stools caused by previous radiation therapy to the abdomen and pelvis.

DiarrheaRadiation Enteritis

Radiation Therapy Oncology Group174 participantsStarted Jun 1999

Birmingham, Alabama, United States • Huntsville, Alabama, United States • Huntsville, Alabama, United States +257 more locations

Open-Label Study of OTO-201 for Treatment of AOMT

Pentosan Polysulfate in Treating Patients With Gastrointestinal Disturbance Caused by Radiation Therapy

Find Trials by Condition in California

Study of Pegilodecakin (LY3500518) With FOLFOX Compared to FOLFOX Alone Second-line Tx in Participants With Metastatic Pancreatic Cancer

One Week Aligner Evaluation

Study the Efficacy and Safety of PTK 0796 in Patients With Complicated Skin and Skin Structure Infection (CSSSI)

Rovalpituzumab Tesirine in Delta-Like Protein 3-Expressing Advanced Solid Tumors

Efficacy & Safety of RPh201 Treatment in Patients With Previous Nonarteritic Anterior Ischemic Optic Neuropathy (NAION)

KPI-121 1% Versus Prednisolone for the Treatment of Inflammation Following Cataract Surgery in Children

Extension Study of Ataluren (PTC124) in Cystic Fibrosis

Randomized Phase 2 Trial of Axitinib and TRC105 Versus Axitinib Alone in Patients Renal Cell Carcinoma

A Study for Participants With Relapsed Cutaneous T-Cell Lymphoma

A Study of ARRY-371797 in Patients With Active Ankylosing Spondylitis

Childhood Absence Epilepsy Rx PK-PD-Pharmacogenetics Study

Safety and Biomarker Study of EPI-589 in Participants With Amyotrophic Lateral Sclerosis (ALS)

Clinical Trial to Evaluation the Safety and Efficacy of GR-MD-02 for the Treatment of Liver Fibrosis and Resultant Portal Hypertension in Patients With Nash Cirrhosis

TroVax® In Subjects With Hormone Refractory Prostate Cancer (HRPC)

MLD10 in the Prevention of Migraine in Adults

BARD® Study of LIFESTREAM™ Balloon Expandable Covered Stent Treating Iliac Arterial Occlusive Disease

A Study of Baricitinib (LY3009104) in Participants With Primary Biliary Cholangitis Who do Not Respond or Cannot Take UDCA

A Study of ARRY-334543 in Patients With Advanced Cancer