Clinical Trials in California

Showing 2921-2940 of 9,745 trials

A Study of SGN-ALPV in Advanced Solid Tumors

NCT05229900

This study will test the safety of a drug called SGN-ALPV in participants with solid tumors. It will also study the side effects of this drug. A side effect is anything a drug does to your body besides treating your disease. Participants will have solid tumor cancer that has spread through the body (metastatic) or cannot be removed with surgery (unresectable). This study will have three parts. Parts A and B of the study will find out how much SGN-ALPV should be given to participants. Part C will use the dose and schedule found in Parts A and B to find out how safe SGN-ALPV is and if it works to treat solid tumor cancers.

Ovarian NeoplasmsEndometrial NeoplasmsCarcinoma, Non-Small-Cell Lung+4 more

Seagen Inc.43 participantsStarted Apr 2022

Fresno, California, United States • New Haven, Connecticut, United States • Wellington, Florida, United States +10 more locations

RECRUITINGNA44 miles

Rising Tide - Amniotic Tissue(s) Treatments for Chronic Diabetic Foot Ulcers

NCT06681428

The purpose of this clinical investigation is to evaluate the safety and efficacy of Amnion/Chorion/Amnion allograft , Amnion/Chorion allograft, and/or Amnion/Amnion allograft, plus Standard of Care (SOC) each versus SOC alone in the treatment of chronic non-healing diabetic foot ulcers (DFU) after 12 weeks of treatment.

Diabetic Foot Ulcer (DFU)Chronic Foot Ulcers

Tides Medical240 participantsStarted Nov 2024

Fresno, California, United States • Los Angeles, California, United States • Los Angeles, California, United States +6 more locations

A Study of SGN-ALPV in Advanced Solid Tumors

Rising Tide - Amniotic Tissue(s) Treatments for Chronic Diabetic Foot Ulcers

Find Trials by Condition in California

Framing Eighteen Coils in Cerebral Aneurysms Trial

Clinical Trial to Assess Efficacy and Safety of the Human Anti-CD38 Antibody Felzartamab (MOR202) in IgA Nephropathy

Study on BI 54903 (Inhaled Corticosteroid) Administered Twice Daily Via Respimat Inhaler in Patients With Asthma Inadequately Controlled on Medium Dose Inhaled Corticosteroid (ICS).

Repigmentation of Stable Vitiligo Lesions Using Spray-On Skin™ Cells

A Study of Participants with Β-Thalassemia Treated with Betibeglogene Autotemcel

ATHN 7: Hemophilia Natural History Study

TK216 in Patients With Relapsed or Refractory Ewing Sarcoma

A Study of AK117 in Combination With Azacitidine in Patients With Myelodysplastic Syndromes

(Concerto) Study of BLU-451 in Advanced Cancers With EGFR Exon 20 Insertion Mutations

A Study to Evaluate the Pharmacokinetics, Safety and Tolerability of Upadacitinib in Pediatric Participants With Severe Atopic Dermatitis

Filgotinib in Long-Term Extension Study of Adults With Ulcerative Colitis

A Study of ERAS-007 in Patients With Advanced Gastrointestinal Malignancies

A Clinical Trial to Evaluate the Safety, Tolerability, and Pharmacokinetics of PGDM1400LS Alone and in Combination With VRC07-523LS and PGT121.414.LS in Healthy, HIV-uninfected Adult Participants

Selumetinib and Cyclosporine in Treating Patients With Advanced Solid Tumors or Advanced or Metastatic Colorectal Cancer

Open-Label Study of Setmelanotide in Hypothalamic Obesity

A Trial of a Novel XPO1 Inhibitor in Participants With Advanced Solid Tumors

LDK378 Versus Chemotherapy in ALK Rearranged (ALK Positive) Patients Previously Treated With Chemotherapy (Platinum Doublet) and Crizotinib

A Study of the Safety and Tolerability in Participants With PIK3CA-related Overgrowth Spectrum or Proteus Syndrome Who Are Being Treated With Miransertib (MK-7075) in Other Studies (MK-7075-006)