Clinical Trials in California

Showing 2681-2700 of 9,745 trials

Study to Investigate the Safety, Tolerability, Pharmacokinetics, Pharmocodynamics and Preliminary Antitumor Activity of AT-1965 in Patients With Advanced, Refractory or Recurrent Solid Tumors

NCT06234098

This is a first-in-human, multicenter, open-label, dose escalation and dose expansion Phase 1/2 study to determine the MTD and/or the recommended Phase 2 dose (RP2D) and to characterize DLTs of AT-1965 as well as to investigate the safety, pharmacokinetics (PK), pharmacodynamics, and preliminary antitumor activity of AT-1965 in patients with advanced, refractory or recurrent solid tumors (nonresectable and/or metastatic) including mTNBC.

Solid Tumor

Alyssum Therapeutics85 participantsStarted Feb 2024

Scottsdale, Arizona, United States • Bakersfield, California, United States • El Segundo, California, United States +4 more locations

RECRUITINGNA143 miles

AltaValve Pivotal Trial

NCT06465745

This is a prospective, single arm, multicenter, clinical trial designed to evaluate the safety and performance of the AltaValve System for the treatment of mitral regurgitation in a targeted patient population.

Mitral RegurgitationMitral InsufficiencyMitral Valve Incompetence+2 more

4C Medical Technologies, Inc.450 participantsStarted Sep 2024

Phoenix, Arizona, United States • Phoenix, Arizona, United States • Tucson, Arizona, United States +26 more locations

Study to Investigate the Safety, Tolerability, Pharmacokinetics, Pharmocodynamics and Preliminary Antitumor Activity of AT-1965 in Patients With Advanced, Refractory or Recurrent Solid Tumors

AltaValve Pivotal Trial

Find Trials by Condition in California

A Study of Ustekinumab in Participants With Active Systemic Lupus Erythematosus

A Study to Evaluate the Efficacy and Safety of JNJ-42847922 as Adjunctive Therapy to Antidepressants in Adult Participants With Major Depressive Disorder Who Have Responded Inadequately to Antidepressant Therapy

A Study of Encapsulated Cell Technology (ECT) Implant for Participants With Early Stage Retinitis Pigmentosa

Precision-T: A Study of Orca-T in Recipients Undergoing Allogeneic Transplantation for Hematologic Malignancies

Ferric Citrate and Chronic Kidney Disease in Children

Azacitidine and Entinostat in Treating Patients With Advanced Breast Cancer

IDP-023 g-NK Cells Plus Ocrelizumab in Patients With Progressive Multiple Sclerosis

ShOrt neCK AAA RAndomized Trial - ESAR and FEVAR: SOCRATES

A Study of Seltorexant in Participants With Probable Alzheimer's Disease

A Study of Paliperidone Palmitate 6-Month Formulation

Expanded Access for Cancer Treatment With Balstilimab (AGEN2034) and Zalifrelimab (AGEN1884)

Study to Evaluate Safety and PK of CHS-006 in Combination With Toripalimab in Patients With Advanced Solid Tumors

A Study of Insulin Efsitora Alfa (LY3209590) as a Weekly Basal Insulin Compared to Insulin Glargine in Adult Participants With Type 2 Diabetes on Multiple Daily Injections

A Study Comparing Daratumumab, Lenalidomide, and Dexamethasone With Lenalidomide and Dexamethasone in Relapsed or Refractory Multiple Myeloma

A Phase 1/2, First-in-Human Dose Escalation/Expansion Study to Evaluate the Safety, Tolerability and Preliminary Efficacy of a Subretinal Injection of SB-007 in Subjects With Stargardt Disease (STGD1)

A Long-term, Safety and Efficacy Study of Intranasal Esketamine in Treatment-resistant Depression

Comparison of Alignment Achieved Using the VELYS Robotic-Assisted Solution Versus Manual Instrumentation in Total Knee Arthroplasty

A Study of Suboptimally Controlled Participants Previously Taking Injectable DMDs for RMS (CLICK-MS)