Clinical Trials in Boston

Showing 1901-1920 of 15,299 trials

A Study of FX-909 in Patients With Advanced Solid Malignancies, Including Advanced Urothelial Carcinoma

NCT05929235

The goal of this clinical trial is to study the safety and tolerability in all advanced solid tumors, including advanced urothelial carcinoma. The main question\[s\] it aims to answer are: * Is FX-909 safe and tolerable, as a monotherapy and in combination with Pembrolizumab * What is the right dose level for patients Participants will be asked to take FX-909 daily in tablet form, or FX-909 daily and Pembrolizumab every 3 weeks, and record any outcomes from taking the drug. Participants will also be asked to return for multiple site visits for various blood tests and to collect blood and tumor samples as well as have regular CT/MRI scans.

Advanced Urothelial CarcinomaOral Drug AdministrationOpen Label

Flare Therapeutics Inc.120 participantsStarted Aug 2023

San Francisco, California, United States • New Haven, Connecticut, United States • Chicago, Illinois, United States +8 more locations

Active Not RecruitingNA< 1 mile

VITamin D and OmegA-3 TriaL: Interrelationship of Vitamin D and Vitamin K on Bone (VITAL)

NCT04573946

Vitamin D supplements are widely promoted for bone health. Both vitamin D and vitamin K are important for deposition of calcium in bone, but little is known about the relationship of vitamin K status and bone health.

Bone DensityBone HealthFractures

Brigham and Women's Hospital25,871 participantsStarted Jul 2019

Boston, Massachusetts, United States

A Study of FX-909 in Patients With Advanced Solid Malignancies, Including Advanced Urothelial Carcinoma

VITamin D and OmegA-3 TriaL: Interrelationship of Vitamin D and Vitamin K on Bone (VITAL)

Find Trials by Condition in Boston

A Novel Vaccine (EO2463) as Monotherapy and in Combination, for Treatment of Patients With Indolent Non-Hodgkin Lymphoma

Combination Chemotherapy With or Without Autologous Stem Cell Transplant in Treating Patients With Central Nervous System B-Cell Lymphoma

PDT For Induction Therapy For Head And Neck Cancer

Tuvusertib (M1774) in Participants With Metastatic or Locally Advanced Unresectable Solid Tumors (DDRiver Solid Tumors 301)

Testing the Addition of the Anti-cancer Viral Therapy Telomelysin™ to Chemoradiation for Patients With Advanced Esophageal Cancer and Are Not Candidates for Surgery

Personalized Risk Estimation for Crohn's Disease (PRE-Crohn's): Implementation and Feasibility

GDNF Gene Therapy for Multiple System Atrophy

Improving Sleep With a Digital Cognitive Behavioral Therapy for Insomnia Application

A Study of Modakafusp Alfa Together With Daratumumab Adults With Relapsed or Refractory Multiple Myeloma

A Study to Evaluate the Efficacy and Safety of Autogene Cevumeran (RO7198457) in Combination With Pembrolizumab Versus Pembrolizumab Alone in Participants With Previously Untreated Advanced Melanoma.

EMG Biofeedback Treatment for Chronic Low Back Pain, Cancer Pain and Migraines

Detrusor Nerve Radiofrequency Ablation for Overactive Bladder in Women

Phase 3 Randomized, Modified Double-blind, Active-controlled Safety Study on vYF in Adults

A Study of Tiragolumab in Combination With Atezolizumab Compared With Placebo in Combination With Atezolizumab in Patients With Previously Untreated Locally Advanced Unresectable or Metastatic PD-L1-Selected Non-Small Cell Lung Cancer

Abbott Structural Heart Device Registry

Safety and Effectiveness of the Globe® Pulsed Field System for Treating Patients With Symptomatic Paroxysmal or Persistent Atrial Fibrillation

Dose-finding Study of SAR443122 in Adult Participants With Ulcerative Colitis

Prospective Study Evaluating the Treatment Outcomes for Localised Recurrent, Resectable Retroperitoneal Liposarcoma