Clinical Trials in Boston

Showing 12781-12800 of 17,836 trials

A Safety Study of SGN-CD33A in AML Patients

NCT01902329

This study will examine the safety profile of vadastuximab talirine (SGN-CD33A) administered as a single agent and in combination with a hypomethylating agent (HMA). The main purpose of the study is to find the maximum tolerated dose (MTD, which is the highest dose that does not cause unacceptable side effects) of SGN-CD33A in patients with acute myeloid leukemia (AML). The MTD will be determined by observing the dose-limiting toxicities (the side effects that prevent further increases in dose) of SGN-CD33A. In addition, the pharmacokinetic profile and anti-leukemia activity of SGN-CD33A will be assessed.

Acute Myelogenous LeukemiaAcute Myeloid LeukemiaAcute Promyelocytic Leukemia

Seagen Inc.195 participantsStarted Jul 2013

Birmingham, Alabama, United States • Duarte, California, United States • Tampa, Florida, United States +11 more locations

COMPLETEDPhase 2< 1 mile

Recombinant Human Prolactin for Lactation Induction

NCT00181610

The purpose of the study is to assess the safety and determine the effects of the hormone prolactin on lactation (breast milk production).

Lactation

Massachusetts General Hospital11 participantsStarted Sep 2004

Boston, Massachusetts, United States

A Safety Study of SGN-CD33A in AML Patients

Recombinant Human Prolactin for Lactation Induction

Find Trials by Condition in Boston

Simvastatin Therapy for Moderate and Severe COPD

Effects of Atorvastatin on Myonecrosis

PAVES: Pegfilgrastim Anti-vascular Endothelial Growth Factor (VEGF) Evaluation Study

IMGN529 in Treating Patients With Relapsed or Refractory Non-Hodgkin's Lymphoma and Chronic Lymphocytic Leukemia

Ramucirumab or Anti-PDGFR Alpha Monoclonal Antibody IMC-3G3 in Treating Patients With Recurrent Glioblastoma Multiforme

Perifosine in Patients With Relapsed/Refractory Waldenstrom's Macroglobulinemia

Study to Assess Best Corrected Visual Acuity (BCVA) in Patients With Neovascular Age-Related Macular Degeneration (AMD) Who Are Administered VEGF Trap-Eye (Intravitreal Aflibercept Injection)

OCT Screening for Diabetic Macular Edema at Primary Diabetes Care Visits

Comprehensive Cardiothoracic Dual Source CT for the Early Triage of Patients With Acute Chest Pain

Study of Ozanezumab (GSK1223249) Versus Placebo in the Treatment of Amyotrophic Lateral Sclerosis

Efficacy of Panobinostat in Patients With Relapsed and Bortezomib-refractory Multiple Myeloma

REDECT 2: REnal Masses: Pivotal Trial to DEteCT Clear Cell Renal Cell Carcinoma With PET/CT

Gemcitabine in Treating Patients With Recurrent or Persistent Endometrial Cancer

Implementation of a Molecular Diagnostic for Pediatric Acute Gastroenteritis: The FilmArray GI Panel IMPACT Study

A Study to Compare the Safety of Rivaroxaban Versus Acetylsalicylic Acid in Addition to Either Clopidogrel or Ticagrelor Therapy in Participants With Acute Coronary Syndrome

Efficacy and Safety of Atacicept in Systemic Lupus Erythematosus

GP2013 Treatment in Patients With Active Rheumatoid Arthritis, Previously Treated With Rituxan® or MabThera®

A Study of Mircera in Anemic Patients With Chronic Kidney Disease Not Yet on Dialysis.