Clinical Trials in Boston

Showing 12641-12660 of 17,836 trials

Combination Therapy Compared With Single-Drug Therapy in Patients With Cardiac Diseases

NCT00115349

The purpose of this study is to determine whether left ventricular function improves more rapidly with deferoxamine (DFO) and deferiprone (L1) combination therapy than with DFO monotherapy in patients with thalassemia and decreased ejection fractions. Secondary aims include evaluating changes in myocardial iron burden using T2\* and estimating the relative incidence and severity of chelator-induced toxicity.

Cardiovascular DiseasesHeart DiseasesBeta-Thalassemia

Carelon Research20 participantsStarted Jun 2005

Los Angeles, California, United States • Oakland, California, United States • Chicago, Illinois, United States +3 more locations

COMPLETED< 1 mile

Third International Study on Mechanical Ventilation

NCT01093482

The objective of this study is to obtain a better understanding of the spectrum of use of mechanical ventilation in intensive care units: 1. Main analysis: To know the all-cause mortality rate in mechanically ventilated patients 2. Secondary analyses: * To know the current status of mechanical ventilation in the intensive care unit and determine the number and percentage of patients who are admitted to an intensive care unit and require mechanical ventilation. * To compare the results with prior data collected in previous observational studies (1998 and 2004) * Non-invasive positive pressure ventilation * Weaning * Use of adjuvant therapies as steroids or selective digestive decontamination * Sedation including prevalence of delirium in mechanically ventilated patients * Prediction of the duration of mechanical ventilation * Other

Acute Respiratory Failure

Hospital Universitario Getafe8,151 participantsStarted Apr 2010

Iowa City, Iowa, United States • Louisville, Kentucky, United States • Boston, Massachusetts, United States +474 more locations

Combination Therapy Compared With Single-Drug Therapy in Patients With Cardiac Diseases

Third International Study on Mechanical Ventilation

Find Trials by Condition in Boston

Deflazacort Expanded Access Program for Children, Adolescents and Adults With Duchenne Muscular Dystrophy

Dose-Dependent Effects of Erythritol on Endothelial Function in Type 2 Diabetes Mellitus

Abatacept for Treating Adults With Giant Cell Arteritis and Takayasu's Arteritis

Telotristat Etiprate for Carcinoid Syndrome Therapy

Computer-Aided Learning for Managing Stress

Healthy Habits, Happy Homes: An Intervention to Improve Household Routines for Obesity Prevention

Red Blood Cell Transfusion in Patients With Coronary Artery Disease (CAD)

Patient Real-world Clinical, Neurological, Tolerability, and Safety Outcomes for Tecfidera® and Rebif®

An Intervention to Improve Adolescent Headache Self-management

The Ward Study for SeptiCyte® Lab to Distinguish Between Infection-positive and Infection-negative SIRS

Trebananib in Treating Patients With Persistent or Recurrent Endometrial Cancer

Prenatal Screening for Down Syndrome With DNAFirst

Continuation Study of Lapatinib Monotherapy or Lapatinib in Combination With Other Anti-cancer Agents

Extension Study Of Subjects From Study A3921030 For The Prevention Of Acute Rejection In Kidney Transplant Patients

An Open Label Multi-center Extension Study to Evaluate Long-term Safety/ Tolerability of Dovitinib in Patients With Solid Tumors Who Continue to Receive Treatment With Dovitinib (TKI258) in Novartis-sponsored Single Agent Dovitinib Studies Which Fulfilled the Requirements for the Primary Objective

Treatment of Thrombocytopenia in Patients With Chronic Liver DiseaseUndergoing an Elective Procedure

Cardiovascular Improvements With MV ASV Therapy in Heart Failure

Phase 2 Trial of AEZS-108 in Chemotherapy Refractory in Triple Negative Breast Cancer