Clinical Trials in Boston

Showing 12241-12260 of 17,836 trials

SF1126 for Patients With Relapsed or Refractory Neuroblastoma

NCT02337309

SF1126 is a novel inhibitor of PI3 kinase and mTOR that includes an active moiety (consisting of LY294002) linked to an RGDS tetrapeptide that targets the active agent to integrin expressing tissues. In this first pediatric phase 1 trial of SF1126, dose escalation will follow a 3+3 dose escalation design. Once a recommended phase 2 pediatric dose is identified, an expansion cohort of 10 patients with tumors with MYCN amplification, Mycn expression, or Myc expression will be treated. Funding Source - FDA OOPD

Neuroblastoma

New Approaches to Neuroblastoma Therapy Consortium4 participantsStarted Jul 2015

Los Angeles, California, United States • San Francisco, California, United States • Aurora, Colorado, United States +8 more locations

COMPLETEDNA< 1 mile

A Skills-Based Program Delivered Via Secure Live Video to Patients With Acute Musculoskeletal Trauma

NCT03405610

The aims of this study are to test a manualized mind body skills-building program aimed at preventing the development of chronic pain and disability following acute musculoskeletal injury in at-risk patients.

Musculoskeletal InjuryFracture

Massachusetts General Hospital55 participantsStarted Jul 2015

Boston, Massachusetts, United States

SF1126 for Patients With Relapsed or Refractory Neuroblastoma

A Skills-Based Program Delivered Via Secure Live Video to Patients With Acute Musculoskeletal Trauma

Find Trials by Condition in Boston

A 60-seconds Personalized Mindfulness Video Exercise for Patients With Orthopedic Illness

Patient and Caregiver Psychological Functioning Following Neuro-ICU Admission: A Prospective Investigation

Enhancing Equitable and Effective (E-3) Post Traumatic Stress Disorder (PTSD) Disability Assessment

Differential Effects of Various Anesthetic Agents on Cognitive Function in Patients With Alzheimer's Disease

A Study of Oral AT2101 (Afegostat Tartrate) in Treatment-naive Patients With Gaucher Disease

A Long-Term Extension Study of AT2101 (Afegostat Tartrate) in Type 1 Gaucher Patients

Everolimus (RAD001) for Children With Chemotherapy-Refractory Progressive or Recurrent Low-Grade Gliomas

Dabrafenib in Treating Patients With Solid Tumors and Kidney or Liver Dysfunction

Study Evaluating HKI-272 (Neratinib) In Subjects With Advanced Breast Cancer

Phase II Study of Buparlisib + Docetaxel in Advanced or Metastatic Squamous Non-small Cell Lung Cancer (NSCLC) Patients

The Gentle Cardiac Rehabilitation Study

Transfusion Requirements in Cardiac Surgery III

SOLUTION: Study of Oral Liprotamase Unit-Matched Therapy Of Non-Porcine Origin in Patients With Cystic Fibrosis

Pharmacokinetics, Safety, and Efficacy of Elvitegravir/Cobicistat/Emtricitabine/Tenofovir Disoproxil Fumarate Single Tablet Regimen (STR) in Adolescents

Study to Evaluate the Safety and Immune Response of Two-Doses of Candidate Influenza Vaccine GSK 1557484A in Adults

A Study of a Combination of Trastuzumab and Capecitabine With or Without Pertuzumab in Patients With HER2-positive Metastatic Breast Cancer (PHEREXA)

Clinical Assessment of a HYDRAGLYDE® Regimen

Automated Screen for Fetal Aneuploidy