Clinical Trials in Boston

Showing 12181-12200 of 17,836 trials

A Phase Ib/II Study of the Combination of BYL719 Plus AMG 479 in Adult Patients With Selected Solid Tumors

NCT01708161

This was a multi-center, open-label, phase Ib/II study. The aim of the phase Ib part was to estimate the MTD(s) and/or identify the recommended phase II dose(s) (RP2Ds) for the combination of BYL719 and AMG 479 (ganitumab), followed by the phase II part to assess the clinical efficacy and to further assess the safety of the combination in selected patient populations. Patients were to be treated until progression of disease, unacceptable toxicity develops, or withdrawal of informed consent, whichever occurred first. All patients were to be followed up. At a minimum, patients must have completed the safety follow-up assessments 30 days after the last dose of the study treatment.

PIK3CA Mutated Advanced Solid TumorsPIK3CA Amplified Advanced Solid Tumors

Novartis Pharmaceuticals47 participantsStarted Nov 2012

Los Angeles, California, United States • Boston, Massachusetts, United States • New York, New York, United States +7 more locations

COMPLETEDPhase 3< 1 mile

Cognition in the Study of Tamoxifen and Raloxifene

NCT00687102

The purpose of this study is to assess the effects of tamoxifen and raloxifene on cognitive aging in selected cognitively-healthy women.

CognitionAging

Wake Forest University1,498 participantsStarted Oct 2001

Phoenix, Arizona, United States • Tucson, Arizona, United States • Camp Pendleton, California, United States +131 more locations

A Phase Ib/II Study of the Combination of BYL719 Plus AMG 479 in Adult Patients With Selected Solid Tumors

Cognition in the Study of Tamoxifen and Raloxifene

Find Trials by Condition in Boston

A Phase 2 Multicenter Randomized Clinical Trial of CNTF for MacTel

The Effect of Tooth Position During Orthodontic Treatment on the Apnea/ Hypopnea Index (AHI)

Long-term Observational Study in HIV Subjects Exposed to EGRIFTA®

Chocolate Balloon Angioplasty Registry

Sequential Angiogenic Blockade for the Treatment of Recurrent Mullerian Malignancies

Vorinostat, Carboplatin and Gemcitabine in Women With Recurrent, Platinum-Sensitive Ovarian Cancer

Radiation Therapy Compared With Chemotherapy and Radiation Therapy in Treating Patients With Newly Diagnosed Primary Central Nervous System (CNS) Germ Cell Tumor

A Randomized Clinical Trial To Study Losartan On Endothelial Dysfunction and Insulin Resistance In Obese Patients

Product Evaluation for the Effectiveness of the ClearGuard™ HD End Cap

Study to Evaluate the Immunogenicity and Safety of GlaxoSmithKline (GSK) Biologicals' Quadrivalent Influenza Vaccine (GSK2282512A) Compared to Fluzone® Quadrivalent in Children 6 to 35 Months of Age

Chemoembolization, Irinotecan Bead, Second Line Chemotherapy Treatment of Unresectable Metastatic Colorectal Cancer

Small Monetary Incentives to Promote Exercise (Exercise4Good; EX4G)

Study of Room Air Versus 60% Oxygen for Resuscitation of Premature Infants

A Phase 3 Study Comparing the Effects of Intravenous Epoetin Hospira and Epoetin Alfa [Epogen] (Amgen) in Patients With Chronic Renal Failure Requiring Hemodialysis and Receiving Epoetin Maintenance Treatment. AiME - Anemia Management With Epoetin

Dose-Escalation Study of ABBV-838, an Antibody Drug Conjugate, in Subjects With Relapsed and Refractory Multiple Myeloma

The Safety and Effectiveness of UroLift: LIFT Pivotal Study

OPTIMA: Efficacy of Optimized Re-treatment and Step-up Therapy With Omalizumab in Chronic Spontaneous Urticaria (CSU) Patients

A Study Comparing Two Treatments for Infants With Hydrocephalus