Clinical Trials in Boston

Showing 11861-11880 of 17,836 trials

Safety Study of Oral MGCD265 Administered Without Interruption to Subjects With Advanced Malignancies

NCT00697632

In this study, MGCD265, a new anticancer drug under investigation, is given daily to patients with advanced malignancies to study its safety profile.

Advanced Cancer

Mirati Therapeutics Inc.180 participantsStarted Jun 2008

Duarte, California, United States • Orange, California, United States • San Diego, California, United States +16 more locations

COMPLETEDNA< 1 mile

Evaluation of Cardiopulmonary Diseases by Ultrasound

NCT02248831

Historically, ultrasound imaging of the lung parenchyma has been challenging because of the high total ultrasound energy attenuation and scattering by the air in the lungs. However, recent technological advancements have allowed for rapid assessment of various pulmonary diseases via the use of lung ultrasound. Furthermore, it has been shown that clear reproducible Doppler signals can be recorded from the lung parenchyma by means of a pulsed Doppler ultrasound system incorporating a special signal-processing package. The LDS may contain information of significant diagnostic and physiological value regarding the pulmonary parenchyma and vasculature, as well as the cardio-vascular system in general. In a pilot clinical validation study of patients with acute decompensated heart failure (ADHF) patients, LDS signals unique to ADHF patients were identified, that superpose on the normal Lung Doppler Signals (unpublished data). These are high velocity "disorganized" variable signals that are not synchronous with the cardiac cycle but rather sometimes with respiration.

DyspneaAcute Decompensated Heart Failure

Echosense Ltd.600 participantsStarted Sep 2014

Boston, Massachusetts, United States

Safety Study of Oral MGCD265 Administered Without Interruption to Subjects With Advanced Malignancies

Evaluation of Cardiopulmonary Diseases by Ultrasound

Find Trials by Condition in Boston

Yoga vs. Physical Therapy vs. Education for Chronic Low Back Pain in Minority Populations

ESCAPE Migraine Trial

Quartet 1457Q Left Ventricular (LV) Lead Investigational Device Exemption (IDE) Study

Double-Blind, Placebo-Controlled Study to Evaluate 3 Doses of a Novel Tetracycline in the Treatment of Facial Acne Vulgaris

Effects of a Single-session Implicit Theories of Personality Intervention on Early Adolescent Psychopathology

MR Guided Focused Ultrasound Treatment of Uterine Fibroids With Enhanced Sonication

MultiPoint Pacing IDE Study

The Effect of Oral PhenazopyrIdine on Perioperative Voiding After Mid-urethral sliNg (EPIPhANy Study)

Evaluation of microMend Device to Close Lacerations

Aortic or Mitral Valve Replacement With the Biocor and Biocor Supra

A Safety and Effectiveness Study of a New Multi-Purpose Contact Lens Care Solution

Helicobacter Pylori Sample Collection Protocol Post Therapy Subjects

Study of Topical ABI-1968 in Subjects With Precancerous Anal Lesions Resulting From Human Papillomavirus (HPV) Infection

MediGuide Registry

Salivary Gland Surgery Before Radiation Therapy in Preventing Radiation-Caused Xerostomia in Patients With Head and Neck Cancer

Disability Severity Scale (DSI) and Hereditary Motor and Sensory Neuropathy Overall Disability Scale (HMSN-R-ODS)

Patient-reported Outcome Scale in Acute Pancreatitis

Implementation of a Web Based Real Time Clinical Decision Support Tool.