Clinical Trials in Boston

Showing 11701-11720 of 17,836 trials

Changing Pediatric Office Systems Nationally to Address Parental Tobacco Use

NCT01882348

The proposed study is a Cluster Randomized Controlled Trial designed to test the sustainability of a previously developed, tested, effectively implemented tobacco control strategy-the CEASE intervention, employing state of the art tobacco dependence treatment for parents who smoke.

Tobacco Dependence

Massachusetts General Hospital3,888 participantsStarted Apr 2015

Boston, Massachusetts, United States

COMPLETEDEARLY Phase 1< 1 mile

Oxytocin Effects on Food Motivation Pathways

NCT02276677

Oxytocin is a peptide hormone produced in the brain that regulates food intake. However, the mechanisms for this effect in humans is not yet clear. In this study, the investigators will therefore examine the effect of a single dose of intranasal oxytocin (compared to placebo) on levels of appetite-regulating hormones and functional magnetic resonance imaging activation of areas of the brain involved in food motivation.

Overweight and Obesity

Massachusetts General Hospital10 participantsStarted Oct 2014

Boston, Massachusetts, United States

COMPLETEDPhase 2< 1 mile

The PRONTO Study, a Global Phase 2b Study of NEOD001 in Previously Treated Subjects With Light Chain (AL) Amyloidosis

NCT02632786

This is a global, multicenter, Phase 2b, randomized, double-blind, placebo-controlled, two-arm, parallel-group efficacy and safety study of NEOD001 as a single agent administered intravenously in adults with AL amyloidosis who had a hematologic response to previous treatment for their amyloidosis (e.g., chemotherapy, autologous stem cell transplant \[ASCT\]) and have persistent cardiac dysfunction.

AL Amyloidosis

Prothena Biosciences Ltd.129 participantsStarted Mar 2016

Duarte, California, United States • Stanford, California, United States • Denver, Colorado, United States +37 more locations

Changing Pediatric Office Systems Nationally to Address Parental Tobacco Use

Oxytocin Effects on Food Motivation Pathways

The PRONTO Study, a Global Phase 2b Study of NEOD001 in Previously Treated Subjects With Light Chain (AL) Amyloidosis

Find Trials by Condition in Boston

Using Spectrally Encoded Confocal Microscopy (SECM) to Visualise the Esophagus Using an SECM Probe

Evaluate the Use of Optical Frequency Domain Imaging (OFDI) for Celiac Disease in Children, Adolescents and Young Adults

Qualitative Research to Explore Treatment Preference in Pulmonary Arterial Hypertension (PAH) Subjects

A Randomized Clinical Trial of Culturally Tailored MI

Safety And Efficacy of Sofosbuvir/Velpatasvir/Voxilaprevir Fixed-Dose Combination for 12 Weeks in Adults Who Participated in a Prior Gilead-Sponsored HCV Treatment Study

Evaluating Ventricular Arrhythmia in Subjects With Implantable Cardioverter Defibrillator or Cardiac Resynchronization Therapy-Defibrillator

Interactive Digital Intervention to Prevent Violence Among Young Adults

Safety, Tolerability and Pharmacokinetics of Multiple Rising Doses of Ixazomib in Lupus Nephritis (LN)

An Efficacy and Safety Study of LYC-30937-EC in Subjects With Active Ulcerative Colitis

Efficacy and Safety of AN2690 Topical Solution to Treat Onychomycosis of the Toenail

Frequency of Screening and SBT Technique Trial

A Clinical Trial Assessing The Impact Of Inhaled Insulin On Glucose Control In Patients With Type 2 Diabetes Mellitus

Seeing-Moving-Playing: Early Rehabilitation Utilizing Visual and Vestibular Technology Following Traumatic Brain Injury

A Phase I, Multicenter Dose Escalation Study in Patients With Hairy Cell Leukemia

Study To Assess Pharmacokinetics, Safety & Efficacy of Anidulafungin When Treating Children With Invasive Candidiasis

A Retrospective Study of the Natural History of Patients With Severe Perinatal and Infantile Hypophosphatasia (HPP)

Increasing Exercise Capacity of Patients With Heart Failure by Wii Gaming