Clinical Trials in Boston

Showing 10501-10520 of 17,836 trials

EEG Studies of Ketamine General Anesthesia

NCT03553758

We are doing this research study to find out how and where ketamine acts in the brain. Ketamine is an anesthetic (a drug or agent used to decrease or eliminate the feeling of pain by putting you in an unconscious state). We will look at the brain using a machine that records the brain's electrical activity, called an electroencephalogram (EEG). We will assess how it impacts patient's pain responses.

Anesthesia

Massachusetts General Hospital16 participantsStarted Nov 2018

Boston, Massachusetts, United States

COMPLETEDPhase 3< 1 mile

Phase III Study of BKM120/Placebo With Fulvestrant in Postmenopausal Patients With Hormone Receptor Positive HER2-negative Locally Advanced or Metastatic Breast Cancer Refractory to Aromatase Inhibitor

NCT01610284

This study was a multi-center, randomized, double-blind, placebo controlled Phase III study to determine the efficacy and safety of treatment with buparlisib plus fulvestrant versus fulvestrant plus placebo in postmenopausal women with hormone Receptor-positive (HR-positive), human epidermal growth factor receptor 2-negative (HER2-negative), locally advanced or metastatic breast cancer (MBC) whose disease has progressed on or after aromatase inhibitor (AI) treatment.

Breast Cancer

Novartis Pharmaceuticals1,147 participantsStarted Aug 2012

Mobile, Alabama, United States • Phoenix, Arizona, United States • Fayetteville, Arkansas, United States +265 more locations

EEG Studies of Ketamine General Anesthesia

Phase III Study of BKM120/Placebo With Fulvestrant in Postmenopausal Patients With Hormone Receptor Positive HER2-negative Locally Advanced or Metastatic Breast Cancer Refractory to Aromatase Inhibitor

Find Trials by Condition in Boston

Follow up 18F-AV-1451 Scan in Confirmatory Cohort Subjects From Study 18F-AV-1451-A05

Regorafenib in Patients With Metastatic and/or Unresectable Gastrointestinal Stromal Tumor

Telbivudine in Adults Previously Treated in Idenix-Sponsored Telbivudine Studies

Trial of Venetoclax (ABT-199) and Dexamethasone for Relapsed or Refractory Systemic AL Amyloidosis

Glembatumumab Vedotin in Treating Patients With Metastatic or Locally Recurrent Uveal Melanoma

Investigation of Exercise Training-Induced Myokines and Adipolkines in Humans

Study of Efficacy and Safety of Brodalumab in Subjects With Psoriatic Arthritis

Study Evaluating Oral MOA-728 For The Treatment Of OIBD In Subjects With Chronic Non-Malignant Pain

Effects of Arm Cycling and Leg Cycling on Postprandial Blood Glucose Levels in Healthy Persons

A Safety and Efficacy Study of Farletuzumab in Participants With Adenocarcinoma of the Lung

A Study of Pegylated Interferon Alfa-2A in Combination With Lamivudine or Entecavir Compared With Untreated Control Group in Children With Hepatitis B Envelope Antigen (HBeAg)-Positive Chronic Hepatitis B (CHB) in the Immune-Tolerant Phase

LEO 90100 Twice Weekly Maintenance Regimen for Psoriasis Vulgaris

Active Reference (Fluoxetine) Fixed-dose Study of Vortioxetine in Paediatric Patients Aged 12 to 17 Years With Major Depressive Disorder (MDD)

Safety and Efficacy of BAY94-9027 in Previously Treated Male Children With Haemophilia A

Dose Ranging Study to Evaluate Immunogenicity and Safety of Adjuvanted or Non-adjuvanted Cell Culture-derived H5N1 Influenza Vaccine in Young Adults (18-40 Years Old)

A Study of Baricitinib (LY3009104) in Patients With Moderate to Severe Atopic Dermatitis

Study of Endorectal Cooling During RARP to Minimize Trauma and Promote Earlier Return to Continence

Long-term Deferiprone Treatment in Patients With Pantothenate Kinase-Associated Neurodegeneration