Clinical Trials in Boston

Showing 10141-10160 of 17,836 trials

A Study of Oral LBH589 in Adult Patients With Advanced Hematological Malignancies

NCT00621244

This study evaluated safety, tolerability, pharmacokinetics and preliminary anti-leukemic or anti-tumor activity of LBH589B in adult patients with advanced hematological malignancies

LymphomaLeukemiaMultiple Myeloma

Novartis Pharmaceuticals175 participantsStarted Mar 2003

Augusta, Georgia, United States • Boston, Massachusetts, United States • Houston, Texas, United States +4 more locations

COMPLETEDPhase 3< 1 mile

A Phase 3 Trial of Brentuximab Vedotin(SGN-35) Versus Physician's Choice (Methotrexate or Bexarotene) in Participants With CD30-Positive Cutaneous T-Cell Lymphoma (ALCANZA Study)

NCT01578499

The purpose of this study is to determine objective response rate (ORR), lasting at least 4 months (ORR4), with brentuximab vedotin in participants with cluster of differentiation antigen 30 positive (CD30+) cutaneous T-cell lymphoma \[mycosis fungoides (MF) and primary cutaneous anaplastic large cell lymphoma (pcALCL) \]compared to that achieved with therapy in the control arm.

Primary Cutaneous Anaplastic Large Cell LymphomaMycosis FungoidesCutaneous T-Cell Lymphoma

Millennium Pharmaceuticals, Inc.131 participantsStarted Jun 2012

Los Angeles, California, United States • Palo Alto, California, United States • Chicago, Illinois, United States +38 more locations

A Study of Oral LBH589 in Adult Patients With Advanced Hematological Malignancies

A Phase 3 Trial of Brentuximab Vedotin(SGN-35) Versus Physician's Choice (Methotrexate or Bexarotene) in Participants With CD30-Positive Cutaneous T-Cell Lymphoma (ALCANZA Study)

Find Trials by Condition in Boston

Safety, Tolerability, Pharmacokinetics and Efficacy of LMB763 in Patients With NASH

Safety, Pharmacokinetics and Preliminary Efficacy Study of CFZ533 in Patients With Primary Sjögren's Syndrome

PAZIT Study for Children and Young Adults With Relapsed or Refractory Sarcoma

A Study in Maintenance Kidney Transplant Recipients Following Conversion to Nulojix® (Belatacept)-Based

Efficacy and Safety of Subcutaneous Secukinumab in Adults With Moderate to Severe Scalp Psoriasis

Topical CP-690,550 For Chronic Plaque Psoriasis

Pharmacodynamics, Safety, Tolerability, and Pharmacokinetics of Two Orally Inhaled Indacaterol Salts in Adult Subjects With Asthma.

Study of Safety and Efficacy of Brolucizumab 6 mg Drug Product Intended for Commercialization in Patients With nAMD

A Safety, Tolerability and Efficacy Study With QBW251 in COPD Patients With QBW251

Triptorelin for Ovary Protection in Childhood Onset Lupus

Safety, Pharmacokinetics and Efficacy of Bimagrumab in Overweight and Obese Patients With Type 2 Diabetes

A Study of CLR325 in Chronic Stable Heart Failure Patients.

MCS110 in Patients With Pigmented Villonodular Synovitis (PVNS)

Safety, Tolerability, and Efficacy of BVS857 in Patients With Spinal and Bulbar Muscular Atrophy

Long-term Extension Study of the Safety and Pharmacokinetics of QCC374 in PAH Patients

ACZ885 for the Treatment of Abdominal Aortic Aneurysm

Efficacy and Safety Study of CSJ148 in Stem Cell Transplant Patients

Efficacy and Safety of LFG316 in Transplant Associated Microangiopathy (TAM) Patients