Clinical Trials in Boston

Showing 9681-9700 of 17,836 trials

Feasibility of mindBEAGLE in Disorders of Consciousness or Locked-In Syndrome

NCT02772302

The primary aims of this study are: 1. To determine the feasibility of deploying mindBEAGLE, a portable, bedside EEG-based system, in the Intensive Care Unit in patients with disorders of consciousness (DOC) or locked-in syndrome (LIS); 2. To determine if mindBEAGLE neurophysiologic markers of cognitive function correlate with bedside behavioral assessments of consciousness; 3. To determine if mindBEAGLE neurophysiologic markers of cognitive function correlate with functional MRI (fMRI) and electroencephalography (EEG) biomarkers of consciousness; 4. To determine if mindBEAGLE can serve as an assistive communication device for people with LIS.

Consciousness DisordersLocked-In Syndrome

Massachusetts General Hospital20 participantsStarted Mar 2016

Boston, Massachusetts, United States

COMPLETEDPhase 1< 1 mile

Safety and Efficacy of Bexagliflozin in Subjects With Moderate Hepatic Impairment

NCT03557658

The purpose of this study is to examine the drug exposure and drug effects on subjects with moderate hepatic impairment after a single oral dose of bexagliflozin tablets, 20mg. The study will also evaluate how safe the study drug is and how well the study drug is tolerated in subjects with moderate hepatic impairment.

Type2 Diabetes Mellitus

Theracos16 participantsStarted Jul 2018

Boston, Massachusetts, United States • Saint Paul, Minnesota, United States

COMPLETEDPhase 2< 1 mile

Subcutaneous CINRYZE With Recombinant Human Hyaluronidase for Prevention of Angioedema Attacks

NCT01756157

The primary objectives of the study are to evaluate the safety, tolerability, and efficacy of two doses of CINRYZE with recombinant human hyaluronidase (rHuPH20) administered by subcutaneous (SC) injection to prevent angioedema attacks.

Hereditary Angioedema (HAE)

Shire47 participantsStarted Feb 2013

Birmingham, Alabama, United States • Scottsdale, Arizona, United States • Bentonville, Arkansas, United States +20 more locations

Feasibility of mindBEAGLE in Disorders of Consciousness or Locked-In Syndrome

Safety and Efficacy of Bexagliflozin in Subjects With Moderate Hepatic Impairment

Subcutaneous CINRYZE With Recombinant Human Hyaluronidase for Prevention of Angioedema Attacks

Find Trials by Condition in Boston

Efficacy and Safety Study of DX-2930 to Prevent Acute Angioedema Attacks in Patients With Type I and Type II HAE

Bupivacaine Effectiveness and Safety in SABER® Trial

2-Year Extension Study of Azeliragon in Subjects With Alzheimer's Disease (STEADFAST Extension)

Safety and Efficacy of NPS 1776 in the Acute Treatment of Migraine Headaches

MAGNOLIA: Extension Study of Patients With Non-infectious Uveitis Who Participated in CLS1001-301

Study To Test Whether PF-00547659 Is Safe And Improves Disease Symptoms In Patients With Crohn's Disease

A Study To Monitor Long-Term Treatment With PF-00547659

Filgotinib Alone and in Combination With Methotrexate (MTX) in Adults With Moderately to Severely Active Rheumatoid Arthritis Who Are Naive to MTX Therapy

Study of Teduglutide Effectiveness in Parenteral Nutrition (PN)-Dependent Short Bowel Syndrome (SBS) Subjects

Safety and Efficacy Study of Teduglutide in Subjects With Short Bowel Syndrome Who Completed Protocol CL0600-004 (NCT00081458)

Pressure Enabled Drug Delivery By Pancreatic Retrograde Venous Infusion For Advanced Pancreatic Carcinoma

The BEACON Study (Breast Cancer Outcomes With NKTR-102)

A Two-Part, Single-Blind, Phase 3 Study Evaluating the Efficacy and Safety of Patiromer for the Treatment of Hyperkalemia (OPAL)

A Study That Tests BI 1467335 in Patients With Diabetic Eye Disease (Diabetic Retinopathy). It Looks at the Way BI 1467335 is Taken up, the Effects it Has, and How Well it is Tolerated.

A Study of Atezolizumab in Advanced Solid Tumors

10+10+30 Infant Vaccines Communication Via Radio in Ethiopia

CINRYZE for the Treatment of Hereditary Angioedema Attacks in Children Under the Age of 12