Clinical Trials in Boston

Showing 8181-8200 of 17,836 trials

The International Diabetes Closed Loop (iDCL) Trial: Protocol 1

NCT02985866

The objective of the study is to assess the efficacy and safety of home use of a Control-to-Range (CTR) closed-loop (CL) system.

Type1 Diabetes Mellitus

University of Virginia127 participantsStarted Oct 2017

Santa Barbara, California, United States • Stanford, California, United States • Aurora, Colorado, United States +4 more locations

COMPLETEDPhase 4< 1 mile

Tocilizumab Plus a Short Prednisone Taper for GCA

NCT03726749

This is an open-label pilot study of tocilizumab (TCZ) 162 mg weekly administered subcutaneously for 52 weeks in combination with 8 weeks of oral prednisone.

Giant Cell Arteritis

Massachusetts General Hospital30 participantsStarted Nov 2018

Boston, Massachusetts, United States

COMPLETEDPhase 1/2< 1 mile

Pilot Phase I/II Study of Amino Acid Leucine in Treatment of Patients With Transfusion-Dependent Diamond Blackfan Anemia

NCT01362595

This study will determine the safety and possibility of giving the amino acid, leucine, in patients with Diamond Blackfan anemia(DBA)who are on dependent on red blood cell transfusions. The leucine is expected to produce a response in patients with DBA to the point where red blood cell production is increased. Red cell transfusions can then be less frequent or possibly discontinued. The investigators will study the side effects, if any, of giving leucine to DBA patients. Leucine levels of leucine will be obtained at baseline and during the study. The drug leucine will be provided in capsule form and taken 3 times a day for a total of 9 months.

Diamond Blackfan AnemiaBlackfan Diamond SyndromeDBA+2 more

Northwell Health55 participantsStarted Jun 2013

Phoenix, Arizona, United States • Palo Alto, California, United States • Indianapolis, Indiana, United States +8 more locations

The International Diabetes Closed Loop (iDCL) Trial: Protocol 1

Tocilizumab Plus a Short Prednisone Taper for GCA

Pilot Phase I/II Study of Amino Acid Leucine in Treatment of Patients With Transfusion-Dependent Diamond Blackfan Anemia

Find Trials by Condition in Boston

The International Diabetes Closed Loop (iDCL) Trial: Protocol 4

A Safety and Efficacy Study of Ibrutinib in Pediatric and Young Adult Participants With Relapsed or Refractory Mature B-cell Non-Hodgkin Lymphoma

Niraparib in Combination With Pembrolizumab in Patients With Triple-negative Breast Cancer or Ovarian Cancer

Anemia Treatment for Advanced Non-Small Cell Lung Cancer (NSCLC) Patients Receiving Chemotherapy

Computer-based Training of Face Recollection to Improve Face Recognition in Developmental Prosopagnosia

Pilot Study of Metformin for Patients With Fanconi Anemia

Study to Assess Darbepoetin Alfa Dosing for the Correction of Anemia in Pediatric Patients With Chronic Kidney Disease

An Open-label Study to Evaluate the Effect of Treatment With Romosozumab or Teriparatide in Postmenopausal Women

A Study to Test Whether Different Doses of BI 456906 Are Effective in Treating Adults With Type 2 Diabetes.

Rivaroxaban for the Prevention of Major Cardiovascular Events in Coronary or Peripheral Artery Disease

Study to Assess in Home Use of Evolocumab (AMG 145) Administration Using Either an Automated Mini-doser or a Prefilled Autoinjector/Pen

Persistence With Prolia® (Denosumab) in Postmenopausal Women With Osteoporosis

Open Label Continuation Treatment Study With Levodopa-Carbidopa Intestinal Gel in Advanced Parkinson's Disease

Pharmacokinetics, Pharmacodynamics, Safety, Tolerability, and Immunogenicity Study of SB16 in Healthy Male Subjects

Safety Study of Nivolumab to Treat Advanced or Metastatic Non-small Cell Lung Cancer

A Prospective, Epidemiological Study to Assess the Disease Burden of Respiratory Syncytial Virus Associated, Suspected Lower Respiratory Tract Infections in Newborns, From 0 to 2 Years of Age and Risk of Development of Wheeze and Asthma From 0 to 6 Years of Age

Gene Therapy for Achromatopsia (CNGA3)