Clinical Trials in Boston

Showing 7701-7720 of 17,836 trials

Evaluation of FDY-5301 in Major Trauma Patients in ICU

NCT04430283

The purpose of this study is to evaluate the efficacy, safety, and pharmacokinetics (PK) of FDY-5301 compared to placebo in major trauma ICU patients at risk of intensive care unit acquired weakness (ICUAW)

ICU Acquired Weakness

Faraday Pharmaceuticals, Inc.8 participantsStarted Sep 2021

Torrance, California, United States • Gainesville, Florida, United States • Boston, Massachusetts, United States +2 more locations

COMPLETEDPhase 3< 1 mile

ACTIV-6: COVID-19 Study of Repurposed Medications - Arm A (Ivermectin 400)

NCT05736861

The purpose of this study is to evaluate the effectiveness of repurposed medications (study drug(s) in reducing symptoms of non-hospitalized participants with mild to moderate COVID-19. Participants will receive either study drug or placebo. They will self-report any new or worsening symptoms or medical events they may experience while taking study drug or placebo. This study is intended to be all remote with no in person visits, unless the study team feels it is in the best interest of a participant to see them in person. Prior and current drug arms are listed on clinicaltrials.gov and will be updated with the activation of any new drug arms. This protocol was originally registered under NCT04885530. Per recent guidance on reporting master protocol research programs (MPRPs), a separate record for Arm A was created.

Covid19

Susanna Naggie, MD1,800 participantsStarted Jun 2021

Gilbert, Arizona, United States • Mesa, Arizona, United States • Peoria, Arizona, United States +84 more locations

Evaluation of FDY-5301 in Major Trauma Patients in ICU

ACTIV-6: COVID-19 Study of Repurposed Medications - Arm A (Ivermectin 400)

Find Trials by Condition in Boston

A Study of ABT-263 in Participants With Relapsed or Refractory Chronic Lymphocytic Leukemia

Radiation Therapy Regimens in Treating Patients With Limited-Stage Small Cell Lung Cancer Receiving Cisplatin and Etoposide

Prostate Cancer Prevention Study for Men With High Grade PIN (Prostatic Intraepithelial Neoplasia)

Study to Assess Safety and Efficacy of the Second Mitochondrial-derived Activator of Caspases (SMAC) Mimetic Debio 1143

Safety and Efficacy of rAAV-hRS1 in Patients With X-linked Retinoschisis (XLRS)

Study of ONCR-177 Alone and in Combination With PD-1 Blockade in Adult Subjects With Advanced and/or Refractory Cutaneous, Subcutaneous or Metastatic Nodal Solid Tumors or With Liver Metastases of Solid Tumors

Study to Evaluate the Efficacy and Safety of CC-90001 in Participants With Non-alcoholic Steatohepatitis (NASH) and Liver Fibrosis

Combination Chemotherapy, PEG-Interferon Alfa-2b, and Surgery in Treating Patients With Osteosarcoma

Sorafenib Tosylate in Treating Patients With Desmoid Tumors or Aggressive Fibromatosis

A Study to Test if TEV-53275 is Effective in Relieving Asthma

Rucaparib in Patients With Locally Advanced or Metastatic Urothelial Carcinoma

Efficacy and Safety APT-1011 in Adult Subjects With Eosinophilic Esophagitis (EoE) (FLUTE-2)

Efficacy and Safety Study of Pegylated Interferon Lambda-1a With Ribavirin and Daclatasvir, to Treat naïve Subjects With Chronic HCV Genotypes 1, 2, 3, and 4 Who Are Co-infected With HIV

A Study to Test Combination Treatments in Participants With Advanced Gastric Cancer

SUVN-502 With Donepezil and Memantine for the Treatment of Moderate Alzheimer's Disease- Phase 2a Study

Natural History Study of Infants and Children With Developmental and Epileptic Encephalopathies

GB5121 in Adult Patients With Relapsed/Refractory CNS Lymphoma

A Study to Learn if Recombinant Human Parathyroid Hormone [rhPTH(1-84)] Can Improve Symptoms and Metabolic Control in Adults With Hypoparathyroidism (BALANCE)