Clinical Trials in Boston

Showing 7041-7060 of 17,836 trials

A Breast Cancer Treatment Decision Aid for Women Aged 70 and Older

NCT02823262

The purpose of this research study is to evaluate a decision aid to help women aged 70 and older decide on treatment for their breast cancer.

Breast CancerEstrogen Receptor Positive Breast CancerNode-negative Breast Cancer+1 more

Beth Israel Deaconess Medical Center65 participantsStarted Jul 2016

Boston, Massachusetts, United States • Boston, Massachusetts, United States

COMPLETEDPhase 3< 1 mile

Chemoembolization With or Without Sorafenib Tosylate in Treating Patients With Liver Cancer That Cannot Be Removed by Surgery

NCT01004978

This randomized phase III trial studies chemoembolization and sorafenib tosylate to see how well they work compared with chemoembolization alone in treating patients with liver cancer that cannot be removed by surgery. Drugs used in chemotherapy, such as doxorubicin hydrochloride, mitomycin, and cisplatin, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Chemoembolization kills tumor cells by carrying drugs directly into blood vessels near the tumor and then blocking the blood flow to allow a higher concentration of the drug to reach the tumor for a longer period of time. Kinase inhibitors, such as sorafenib tosylate may stop the growth of tumor cells by blocking the action of an abnormal protein that signals cancer cells to multiply. It is not yet known whether giving chemoembolization together with sorafenib tosylate is more effective than chemoembolization alone in treating patients with liver cancer.

Hepatocellular CarcinomaUnresectable Hepatocellular Carcinoma

National Cancer Institute (NCI)235 participantsStarted Oct 2009

Birmingham, Alabama, United States • Mobile, Alabama, United States • Scottsdale, Arizona, United States +278 more locations

A Breast Cancer Treatment Decision Aid for Women Aged 70 and Older

Chemoembolization With or Without Sorafenib Tosylate in Treating Patients With Liver Cancer That Cannot Be Removed by Surgery

Find Trials by Condition in Boston

Synuclein-One Study

A Study of Lirentelimab (AK002) in Patients With Active Eosinophilic Esophagitis

A Phase 1b Trial of ATRC-101 in Adults With Advanced Solid Malignancies

Evaluation of Immunobiogram® as a Tool in Adjustment of Immunosuppressant Therapy for Renal Transplant

Safety and Efficacy of Activated Recombinant Human Factor VII in Haemophilia Patients With Inhibitors During and After Major Surgery

Digital Ischemic Lesions in Scleroderma Treated With Oral Treprostinil Diethanolamine

Study Investigating NTLA-5001 in Subjects With Acute Myeloid Leukemia

Clinical Trial of Solanezumab for Older Individuals Who May be at Risk for Memory Loss

VIR-7831 for Inpatients With COVID-19 (An ACTIV-3/TICO Treatment Trial)

Efficacy and Safety of Oxmorphone Extended Release in Chronic Non-malignant Pain

Trial in Non-cystic Fibrosis Bronchiectasis Patients With Chronic Lung Infections Treated With Colistimethate Sodium.

Development of a Questionnaire to Evaluate Patient Expectations for Breast Reconstruction in Women With Breast Cancer or Other Conditions

A Study to Evaluate Patient Preference and Satisfaction of Subcutaneous Administration of the Fixed-Dose Combination of Pertuzumab and Trastuzumab in Participants With HER2-Positive Early Breast Cancer

Planned Semi-Elective Lung Tx Study

Enhanced Triage for COVID-19

Diffusion-Weighted MRI for Liver Metastasis

Study to Evaluate the Effects of RO7496998 (AT-527) in Non-Hospitalized Adult and Adolescent Participants With Mild or Moderate COVID-19

International REACH Forgiveness Intervention