Clinical Trials in Boston

Showing 5941-5960 of 17,836 trials

The Effect of Opioid-Free Anesthesia in TMJ Surgery

NCT04724759

This study aims is to evaluate the effect of opioid free total intravenous anesthesia on postoperative quality of recovery in patients undergoing oral and maxillofacial surgery (OMF) temporomandibular joint (TMJ) surgery.

Temporomandibular Joint Disorders

Massachusetts General Hospital60 participantsStarted Jun 2021

Boston, Massachusetts, United States

Active Not Recruiting< 1 mile

Mechanisms of Cardiac Dysfunction in HIV and the Effect of Statins: a Cardiac MRI Study

NCT03238755

In this study, investigators plan to test whether statins can preserve and/or improve diastolic function among asymptomatic persons with HIV who are on anti-retroviral therapy. Both myocardial fibrosis and myocardial steatosis are thought to contribute to diastolic dysfunction and eventually overt heart failure in HIV. HIV-positive participants will undergo cardiac MRI/MRS imaging studies for the evaluation of myocardial fibrosis and myocardial steatosis prior to initiation of statin or placebo therapy and then two years after initiation of statin or placebo therapy. Traditional markers of cardiovascular (CVD) risk, systemic immune activation/ inflammation, HIV-specific parameters (i.e. CD4 count), and markers of myocardial stretch/injury will be assessed in relation to cardiac MRI/MRS outcomes.

HIV Infections

Massachusetts General Hospital129 participantsStarted Jul 2017

Los Angeles, California, United States • Boston, Massachusetts, United States • Dallas, Texas, United States +1 more locations

COMPLETED< 1 mile

Refining the Shared Decision Making Process Survey in ADHD Medication Decisions

NCT05048186

This is a retrospective observational survey study. We will survey a sample of adult parents or legal guardians who have a child who has been diagnosed with Attention Deficit Hyperactivity Disorder (ADHD) and who discussed ADHD treatment options for their child with a health care provider within the last 2 years. The main goal is to gather evidence of the validity and reliability of the Shared Decision Making Process scale. Secondary goal is to gather evidence on the quality of decisions parents make about their children with ADHD. A third goal is to assess the impact of a Decision Aid on participant knowledge of ADHD treatment options. Participants will be randomized to one of two arms: participants in the intervention arm will review a Decision Aid (patient educational tool) partway through the survey and those in the control arm will not receive any educational materials. All participants will complete survey that includes the Shared Decision Making process survey along with a few other measures. A subset of respondents will also complete a retest survey about two weeks after the initial survey.

ADHD

Massachusetts General Hospital512 participantsStarted Feb 2021

Boston, Massachusetts, United States

The Effect of Opioid-Free Anesthesia in TMJ Surgery

Mechanisms of Cardiac Dysfunction in HIV and the Effect of Statins: a Cardiac MRI Study

Refining the Shared Decision Making Process Survey in ADHD Medication Decisions

Find Trials by Condition in Boston

Aspirin Supplementation for Pregnancy Indicated Risk Reduction In Nulliparas (ASPIRIN)

Integrating Ketamine Effects on Neuronal Molecular Signatures and the Brain Functional and Structural Connectome

Alzheimer's Disease Neuroimaging Initiative 2

Optimal Stimulation Parameters to Disrupt Epileptiform Activity

Examining Cognitive Mechanisms of Clinical Improvement Following Mindfulness Based Therapy for Depressed Individuals

Lentiviral Gene Therapy (Zamtocabtagene Autoleucel) LTFU

Hemodynamic Evaluation of Levosimendan in Patients With PH-HFpEF

Phase II Clinical Trial: Multi-dosing the BCG Vaccine for Fibromyalgia

Study to Evaluate the Efficacy, Safety, and Tolerability of Mirabegron in Older Adult Subjects With Overactive Bladder (OAB)

Irrisept Solution for Instrumented Spine Surgery

Transfusion Requirements in Younger Patients Undergoing Cardiac Surgery

Long-Term Extension Trial of Tildrakizumab to Prove Its Safety in Subjects With Psoriatic Arthritis Who Have Previously Completed Study With Tildrakizumab.

SELECT2: A Randomized Controlled Trial to Optimize Patient's Selection for Endovascular Treatment in Acute Ischemic Stroke

A Study to Evaluate the Efficacy and Safety of Mirabegron Compared to Solifenacin in Patients With Overactive Bladder Who Were Previously Treated With Another Medicine But Were Not Satisfied With That Treatment.

Registry of Subjects With Drug Resistant Epilepsy and Treated With the VNS Therapy System.

A Study of BI 765128 in Patients With an Eye Condition Called Diabetic Macular Ischemia Who Have Received Laser Treatment

Third Enhanced Control of Hypertension and Thrombectomy Stroke Domain Within ACT-GLOBAL Adaptive Platform Trial