Clinical Trials in Boston

Showing 5741-5760 of 17,836 trials

A Study Evaluating the Safety and Efficacy of BEAM-201 in Relapsed/Refractory T-Cell Acute Lymphoblastic Leukemia (T-ALL) or T-Cell Lymphoblastic Lymphoma (T-LL)

NCT05885464

This is a Phase 1/2, multicenter, open-label study to evaluate the safety and efficacy of BEAM-201 in patients with relapsed/refractory T-ALL or T-LL. This study consists of Phase 1 dose-exploration cohorts, Phase 1 dose-expansion cohort(s), a Phase 1 pediatric cohort (will enroll patients ages 1 to \< 12 years), and a Phase 2 cohort.

Lymphoblastic LymphomaT-Cell Lymphoblastic Leukemia/LymphomaLymphoblastic Leukemia

Beam Therapeutics Inc.5 participantsStarted May 2023

Stanford, California, United States • Denver, Colorado, United States • Chicago, Illinois, United States +7 more locations

COMPLETEDPhase 3< 1 mile

Study of 177Lu-PSMA-617 In Metastatic Castrate-Resistant Prostate Cancer

NCT03511664

The primary objective of this study was to compare the two alternate primary endpoints of radiographic progression-free survival (rPFS) and overall survival (OS) in patients with progressive prostate-specific membrane antigen (PSMA)-positive metastatic castration-resistant prostate cancer (mCRPC) who received 177Lu-PSMA-617 in addition to best supportive/best standard of care (BSC/BSoC) versus patients treated with best supportive/best standard of care alone.

Prostate Cancer

Endocyte861 participantsStarted May 2018

Scottsdale, Arizona, United States • Tucson, Arizona, United States • Los Angeles, California, United States +85 more locations

A Study Evaluating the Safety and Efficacy of BEAM-201 in Relapsed/Refractory T-Cell Acute Lymphoblastic Leukemia (T-ALL) or T-Cell Lymphoblastic Lymphoma (T-LL)

Study of 177Lu-PSMA-617 In Metastatic Castrate-Resistant Prostate Cancer

Find Trials by Condition in Boston

Testing Cabozantinib, Crizotinib, Savolitinib and Sunitinib in Kidney Cancer Which Has Progressed

Gamma Light and Sound Stimulation to Prevent Dementia in Cognitively Normal People At Risk for Alzheimer's Disease

Adavosertib, Radiation Therapy, and Temozolomide in Treating Patients With Newly Diagnosed or Recurrent Glioblastoma

Contrast Enhanced Spectral Mammography vs. MRI for Breast Cancer Screening

Ketamine for the Treatment for Alcohol Use Disorder in the ED

Benefits of µCor in Ambulatory Decompensated Heart Failure

Multicenter Trial of Antibiotic Eluting Graft for Promoting New Bone Growth In/near Infected Bone Cavities

Evaluate the Efficacy and Safety of ACP-044 in Subjects With Pain Associated With Osteoarthritis of the Knee

A Study of TAK-861 in Participants With Narcolepsy Type 2

Open-Label Extension Study of Upadacitinib in Adult Participants With Moderate to Severe Atopic Dermatitis

Prophylactic vs Therapeutic Cerebrospinal Fluid Drain Placement During Endovascular Thoracoabdominal Aortic Aneurysm Repair

Emergency Department-Initiated Buprenorphine Validation Network Trial

Study of Nanrilkefusp Alfa Alone and With Pembrolizumab in Adult Patients With Advanced/Metastatic Solid Tumors

Talimogene Laherparepvec With Pembrolizumab in Melanoma Following Progression on Prior Anti-PD-1 Based Therapy (MASTERKEY-115) (Mk-3475-A07/KEYNOTE-A07).

Benefits of Microcor in Ambulatory Decompensated Heart Failure

Computer-based Intervention for Alcohol-using HIV/HCV+ Women

FLExAbility Sensor Enabled Substrate Targeted Ablation for the Reduction of VT Study

Multi-Center Study of GSK2857916 in Combination With Pomalidomide and Dex