Clinical Trials in Boston

Showing 5201-5220 of 17,836 trials

A Study to Evaluate ASP0367 in Participants With Reduced Maximum Oxygen Uptake Due to Poor Systemic Oxygen Extraction

NCT04855201

The purpose of this study is to to evaluate the effect of ASP0367 on improvement of aerobic capacity relative to placebo, as well as evaluate the safety and tolerability of ASP0367 relative to placebo. This study will also evaluate the effect of ASP0367 on improvement of other aerobic capacity parameters relative to placebo, as well as evaluate the effect of ASP0367 on improvement of functional capacity relative to placebo.

Reduced Maximum Oxygen Uptake Due to Poor Systemic Oxygen Extraction

Astellas Pharma Global Development, Inc.31 participantsStarted Jun 2021

Boston, Massachusetts, United States

Active Not RecruitingPhase 3< 1 mile

Relacorilant in Combination With Nab-Paclitaxel in Advanced, Platinum-Resistant, High-Grade Epithelial Ovarian, Primary Peritoneal, or Fallopian-Tube Cancer

NCT05257408

The primary objectives of this study are to evaluate progression-free survival (PFS) by blinded independent central review (BICR) and overall survival (OS) (evaluated independently, as dual primary endpoints) in patients treated with intermittent regimen of Relacorilant in combination with nab-paclitaxel compared with patients treated with nab-paclitaxel monotherapy.

Ovarian NeoplasmFallopian Tube NeoplasmsPeritoneal Neoplasms

Corcept Therapeutics381 participantsStarted Jun 2022

Phoenix, Arizona, United States • Tucson, Arizona, United States • Irvine, California, United States +114 more locations

A Study to Evaluate ASP0367 in Participants With Reduced Maximum Oxygen Uptake Due to Poor Systemic Oxygen Extraction

Relacorilant in Combination With Nab-Paclitaxel in Advanced, Platinum-Resistant, High-Grade Epithelial Ovarian, Primary Peritoneal, or Fallopian-Tube Cancer

Find Trials by Condition in Boston

A Study of Ad-RTS-hIL-12 With Veledimex in Subjects With Glioblastoma or Malignant Glioma

Early Interventional Treatment for Cancer Pain

Study to Evaluate the Efficacy and Safety of Nintedanib (BIBF 1120) + Prednisone Taper in Patients With Radiation Pneumonitis

Calcium Channel Blockade in Primary Aldosteronism

Pediatric Healthy Weight Clinic

Ureteral Stent Placement After Ureteroscopy for Renal Stones: A Randomized Controlled Trial

Pevonedistat, Azacitidine, Fludarabine Phosphate, and Cytarabine in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia or Myelodysplastic Syndrome

Effectiveness of Bilateral PTNS Compared to Unilateral PTNS for the Treatment of Overactive Bladder/Urge Incontinence

Safety and Tolerability of BION-1301 in Healthy Volunteers and Adults With IgA Nephropathy (IgAN)

A Study of Pazopanib With or Without Abexinostat in Patients With Locally Advanced or Metastatic Renal Cell Carcinoma (RENAVIV)

Study of Nab-Paclitaxel and Gemcitabine and Plus/Minus VCN-01 in Patients With Metastatic Pancreatic Cancer

Tritanium® Primary Acetabular Shell Study

Conduction System Pacing Optimized Therapy

The GORE VBX FORWARD Clinical Study: A Comparison of the GORE® VIABAHN® VBX Balloon Expandable Endoprosthesis to Bare Metal Stenting for Patients With Complex Iliac Occlusive Disease

Hairy Cell Leukemia Patient Data Registry

BAsel Syncope EvaLuation (BASEL IX) Study

LITMUS Imaging Study

A Phase 1 Study Evaluating the Safety of TRK-950 in Patients With Advanced Solid Tumors