Clinical Trials in Boston

Showing 4941-4960 of 17,836 trials

Intervening in Food Insecurity to Reduce and Mitigate (InFoRM) Childhood Obesity

NCT05586269

The goals of this study are to 1) pilot the feasibility of a novel meal kit delivery intervention in families and children with food insecurity and obesity and 2) evaluate the implementation of the pilot intervention.

Pediatric ObesityNutrition DisordersOvernutrition, Child+1 more

Boston Children's Hospital59 participantsStarted Feb 2023

Boston, Massachusetts, United States

Active Not RecruitingPhase 1< 1 mile

Testing the Addition of an Anti-cancer Drug, Elimusertib (BAY 1895344) ATR Inhibitor, to the Chemotherapy Treatment (Gemcitabine) for Advanced Pancreatic and Ovarian Cancer, and Advanced Solid Tumors

NCT04616534

This phase I trial identifies the best dose, possible benefits and/or side effects of gemcitabine in combination with elimusertib (BAY 1895344) in treating patients with pancreatic, ovarian, and other solid tumors that have spread to other places in the body (advanced). Gemcitabine is a chemotherapy drug that blocks the cell from making DNA and may kill tumor cells. elimusertib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Giving gemcitabine and elimusertib in combination may shrink or stabilize cancer.

Advanced Fallopian Tube CarcinomaAdvanced Malignant Solid NeoplasmAdvanced Ovarian Carcinoma+19 more

National Cancer Institute (NCI)14 participantsStarted Jun 2021

Bethesda, Maryland, United States • Bethesda, Maryland, United States • Boston, Massachusetts, United States

Intervening in Food Insecurity to Reduce and Mitigate (InFoRM) Childhood Obesity

Testing the Addition of an Anti-cancer Drug, Elimusertib (BAY 1895344) ATR Inhibitor, to the Chemotherapy Treatment (Gemcitabine) for Advanced Pancreatic and Ovarian Cancer, and Advanced Solid Tumors

Find Trials by Condition in Boston

A Personalized Neoantigen Cancer Vaccine in Treatment Naïve, Asymptomatic Patients With IGHV Unmutated CLL.

Soy Nuts and Cardiovascular Risk in Postmenopausal Women

Efficacy and Safety of MSC-NTF (NurOwn) in Participants With Early Symptomatic ALS and Moderate Disease Presentation in ALS (ENDURANCE STUDY)

Multi-Component Breath Alcohol Intervention

NUDGE-EHR Replication Trial at Mass General Brigham

Treatment of Pregnant Women With OUD

Efficacy, Safety and Pharmacokinetics of Rilzabrutinib in Patients With Warm Autoimmune Hemolytic Anemia (wAIHA)

A Registry for People With T-cell Lymphoma

Mycobacteriophage Treatment of Non-tuberculosis Mycobacteria

Assessing the Accuracy of Tumor Biopsies After Chemotherapy to Determine if Patients Can Avoid Breast Surgery

Rucaparib in Treating Patients With Genomic LOH High and/or Deleterious BRCA1/2 Mutation Stage IV or Recurrent Non-small Cell Lung Cancer (A Lung-MAP Treatment Trial)

Study of Nalbuphine HCl ER Tablets in Hemodialysis Patients With Uremic Pruritus

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Antitumor Activity of ADCT-901 in Participants With Selected Advanced Solid Tumors

Safety and Efficacy Study of CFI-402411 in Subjects With Advanced Solid Malignancies

Trial of Efficacy and Safety of NS-229 Versus Placebo in Patients With Eosinophilic Granulomatosis With Polyangiitis

A RCT Evaluating the Clinical Benefit of a Silver Dressing in the Treatment of Venous Leg Ulcers

Prospective Natural History Study of Retinitis Pigmentosa

A Study of Mipasetamab Uzoptirine (ADCT-601) in Participants With Solid Tumors