Clinical Trials in Boston

Showing 261-280 of 15,299 trials

Pain Disengagement Training (Open Pilot)

NCT06870162

The investigators aim to conduct an open pilot trial to determine the initial feasibility of a self-directed writing-based intervention in individuals with chronic musculoskeletal pain and elevated pain catastrophizing. The investigators will assess the feasibility of recruitment, acceptability of the treatment, credibility and participant satisfaction, treatment adherence, and feasibility of assessments following pre-specified benchmarks.

Chronic Musculoskeletal Pain

Massachusetts General Hospital10 participantsStarted Oct 2025

Boston, Massachusetts, United States

SUSPENDEDNA< 1 mile

AXIOS™ Gastroenterostomy for Gastric Outlet Obstruction IDE

NCT06174805

To investigate the safety and technical success of EUS-guided gastroenterostomy (EUS-GE) using the AXIOSTM lumen-apposing Metal Stent for the management of symptoms associated with gastric outlet obstruction from malignant unresectable neoplasm.

Gastric Outlet Obstruction

Boston Scientific Corporation67 participantsStarted Feb 2025

Boston, Massachusetts, United States • Rochester, Minnesota, United States • New York, New York, United States +7 more locations

Pain Disengagement Training (Open Pilot)

AXIOS™ Gastroenterostomy for Gastric Outlet Obstruction IDE

Find Trials by Condition in Boston

A Study of JSB462 (Luxdegalutamide) Plus Lutetium (177Lu) Vipivotide Tetraxetan in Patients With Metastatic Castration Resistant Prostate Cancer (mCRPC)

Efficacy and Safety of Tezepelumab in Patients With Eosinophilic Esophagitis

Ph 2 Elacestrant in ER Positive Uterine Sarcomas

SUPRAME-ACTengine® IMA203 vs. Investigator's Choice of Treatment in Previously Treated, Unresectable or Metastatic Cutaneous Melanoma

Evaluation of AMG 714 for Vitiligo

Anti-Lag-3 (Relatlimab) and Anti-PD-1 Blockade (Nivolumab) Versus Standard of Care (Lomustine) for the Treatment of Patients With Recurrent Glioblastoma

PH 2 Pemigatinib in SDH-deficient GIST

INHALE-1st: Afrezza® For Youth With Newly-Diagnosed Type 1 Diabetes

DT2216 + Paclitaxel in Platinum-Resistant Ovarian Cancer

Mindful Attention to Variability in Everyday Memory

A Study of Metastases Free Survival With Saruparib vs Placebo Added to a Standard RT/ADT in Men With High-risk Prostate Cancer With a BRCA Mutation

Study of Efficacy and Safety of JDQ443 Single-agent as First-line Treatment for Patients With Locally Advanced or Metastatic KRAS G12C- Mutated Non-small Cell Lung Cancer With a PD-L1 Expression < 1% or a PD-L1 Expression ≥ 1% and an STK11 Co-mutation.

Anti-Ly6E Exatecan ADC M7437 in Advanced Solid Tumors

A Study to Learn About the Study Medicine Called PF-08046054/SGN-PDL1V Versus Docetaxel in Adult Participants With Previously-Treated Programmed Cell Death Ligand 1 (PD-L1) Positive Non-Small-Cell Lung Cancer (NSCLC)

Efficacy and Safety of MET097 Once-Weekly in People With Overweight or Obesity

A First-in-human Study to Learn How Safe the Study Drug BAY3375968, an Anti-CCR8 Antibody, is, When Given Alone or in Combination With Pembrolizumab, How it Affects the Body, How it Moves Into, Through, and Out of the Body, and to Find the Best Dose in Participants With Advanced Solid Tumors

Pooled Analysis of Single-arm Studies of Budesonide/Glycopyrronium/Formoterol (BGF) in Routine Care Setting

A Study to Evaluate the Long-Term Safety and Efficacy of JNT-517 in Participants With Phenylketonuria