Clinical Trials in Boston

Showing 2681-2700 of 15,299 trials

Observational Study of the Effect of Ozanimod on Fatigue in Multiple Sclerosis Patients

NCT05319093

Multi-center observational study to assess the short-term response of multiple sclerosis (MS) patients initiated on Ozanimod with respect to fatigue. Patterns of brain changes on brain magnetic resonance imaging (MRI) that might modulate the effect of Ozanimod treatment on fatigue will also be assessed.

FatigueMultiple Sclerosis

Brigham and Women's Hospital26 participantsStarted Apr 2022

Boston, Massachusetts, United States

RECRUITINGPhase 2< 1 mile

Angiotensin-Neprilysin Inhibition in Hemodialysis Initiation

NCT05498181

This randomized placebo-controlled clinical trial will evaluate the effect of sacubitril/valsartan (compared with placebo) on echocardiographic measures of hypervolemia, preservation of residual renal function, and key safety parameters in incident hemodialysis patients.

Hemodialysis

Brigham and Women's Hospital100 participantsStarted Oct 2022

Boston, Massachusetts, United States

COMPLETEDPhase 2< 1 mile

A Study to Evaluate the Safety and Efficacy of CNTX-6970 in Subjects With Knee Osteoarthritis Pain.

NCT05025787

The primary objective of this study is to evaluate the safety and efficacy of CNTX-6970 for the treatment of pain related to OA of the knee compared to placebo. CNTX-6970 is being developed as a new treatment for chronic pain, including painful osteoarthritis of the knee.

Knee Osteoarthritis

Maurizio Fava, MD55 participantsStarted Oct 2021

La Jolla, California, United States • Sacramento, California, United States • Gainesville, Florida, United States +13 more locations

Observational Study of the Effect of Ozanimod on Fatigue in Multiple Sclerosis Patients

Angiotensin-Neprilysin Inhibition in Hemodialysis Initiation

A Study to Evaluate the Safety and Efficacy of CNTX-6970 in Subjects With Knee Osteoarthritis Pain.

Find Trials by Condition in Boston

Safety Study of Cytisinicline in Adult Combustible and/or E-cigarette Smokers

Lenalidomide and Blinatumomab for the Treatment of Relapsed Non-Hodgkin Lymphoma

Optimizing and Advancing SBIRT in Schools

A Trial Comparing Screening Mammography With and Without Assistance From Artificial Intelligence for Breast Cancer Detection and Recall Rates in Adult Patients

CAR-T Cell Therapy for Desensitization in Kidney Transplantation

A Research Study Looking at How Well a Combination of the Medicines Semaglutide and NNC0480-0389 Works in People With Type 2 Diabetes

Family Partner Navigation for Children

Lenalidomide and Dexamethasone With or Without Thalidomide in Treating Patients With Multiple Myeloma

Evaluation of the Paramedic Evaluation for Acute COPD Exacerbation

Carboplatin and Paclitaxel or Oxaliplatin and Capecitabine With or Without Bevacizumab as First-Line Therapy in Treating Patients With Newly Diagnosed Stage II-IV or Recurrent Stage I Epithelial Ovarian or Fallopian Tube Cancer

This Study Aims to Find the Best Dose of BI 907828 (Brigimadlin) in Patients With Different Types of Advanced Cancer (Solid Tumors)

Fluid Management of Acute Decompensated Heart Failure Subjects Treated With Reprieve System (FASTR-II) (IDE-G210258)

Research Study to Look at How Well Semaglutide Works in People Living With Heart Failure, Obesity and Type 2 Diabetes

A Study of Tirzepatide (LY3298176) in Participants With Obesity or Overweight With Weight Related Comorbidities

Assessment of Efficacy and Safety of Durvalumab Plus BCG Compared to the Standard Therapy With BCG in Non-muscle Invasive Bladder Cancer

Albumin Utilization in Adult Cardiac Surgical Patients: Retrospective

ABX464 in Treating Inflammation and Preventing Acute Respiratory Failure in Patients With COVID-19