Clinical Trials in Boston

Showing 2601-2620 of 15,299 trials

Fibroblast Growth Factor Regeneration of Tympanic Membrane Perforations

NCT02307916

A Phase II randomized trial will be initiated to evaluate closure of the perforated tympanic membrane as the primary measureable outcome. The goal is to determine the safety and efficacy of Fibroblast Growth Factor-2 (FGF-2) in the closure of chronic tympanic membrane perforations (TMP). If FGF-2 is topically applied for the treatment of chronic TMP in humans, it is hypothesized it will be safe, tolerable and effective for use as treatment for tympanic membrane perforation. A total of 60 subjects will be recruited.

Tympanic Membrane Perforation

D. Bradley Welling, MD, PhD57 participantsStarted Oct 2016

Boston, Massachusetts, United States • Lackland City, Texas, United States

COMPLETEDNA< 1 mile

Transcranial Photobiomodulation Therapy for the Treatment of Autistic Traits in Children and Adolescents With ADHD

NCT04569058

An open label trial to assess the safety and efficacy of transcranial photobiomodulation (tPBM) in improving autistic traits in ADHD youth.

AutismAttention Deficit Hyperactivity Disorder

Massachusetts General Hospital38 participantsStarted Jan 2021

Boston, Massachusetts, United States

COMPLETEDPhase 2< 1 mile

Imaging Evaluation of PLN-74809 in Participants With IPF (PLN-74809)

NCT05621252

This is a Phase 2a, single -center, randomized, double-blind, placebo-controlled study to evaluate type 1 collagen deposition in the lungs following once-daily treatment with PLN-74809 for 12-weeks. This study is occurring at Massachusetts General Hospital.

Idiopathic Pulmonary Fibrosis

Pliant Therapeutics, Inc.10 participantsStarted Jul 2022

Boston, Massachusetts, United States

Fibroblast Growth Factor Regeneration of Tympanic Membrane Perforations

Transcranial Photobiomodulation Therapy for the Treatment of Autistic Traits in Children and Adolescents With ADHD

Imaging Evaluation of PLN-74809 in Participants With IPF (PLN-74809)

Find Trials by Condition in Boston

Validation of a Novel Cerebellar-striatal Satiety Circuit in Humans

Zanubrutinib and Venetoclax in CLL (ZANU-VEN)

C-BEYOND: Efficacy and Safety of BEM/RZR vs. SOF/VEL in Subjects With Chronic HCV

Study of Inebilizumab in Pediatric Subjects With Neuromyelitis Optica Spectrum Disorder

A Pharmaco-surgical Approach to Reduce Postoperative Atrial Fibrillation After Cardiac Surgery

Agili-C™ Implant Performance Evaluation

Role of Dietary Habits in Efficacy of Bariatric Surgery - Study C

ACALA-R In Predominantly Demyelinating IgM Mediated Neuropathy

A Trial To Find Out If Vidutolimod Together With Cemiplimab Is Safe And If It Works In Adult Participants With Advanced Cancer Or Metastatic Cancer

Targeted Treatment for Advanced Non-Small Cell Lung Cancer That Has Increased Copies of the MET Gene (An Expanded Lung-MAP Treatment Trial)

A Study of Zetomipzomib (KZR-616) in Patients With Active Lupus Nephritis (PALIZADE)

Evaluating Whether an Educational Website Called Current Together After Cancer (CTAC) Improves Follow-up Care for Colorectal Cancer Survivors

CAMPFIRE: A Study of Ramucirumab (LY3009806) in Children and Young Adults With Desmoplastic Small Round Cell Tumor

A Research Study Looking at How Safe it is to Switch From Emicizumab to Mim8 in People With Haemophilia A (FRONTIER 5)

Study of HPN217 in Participants With Relapsed/Refractory Multiple Myeloma MK-4002 (MK-4002-001)

Chyme Reinfusion for Type 2 Intestinal Failure

A Study to Investigate Atezolizumab Subcutaneous in Patients With Previously Treated Locally Advanced or Metastatic Non-Small Cell Lung Cancer