Clinical Trials in Boston

Showing 2461-2480 of 15,299 trials

A Study of JNJ-64619178, an Inhibitor of PRMT5 in Participants With Advanced Solid Tumors, NHL, and Lower Risk MDS

NCT03573310

The purpose of the study is to identify the maximum tolerated dose (MTD) of JNJ-64619178 in participants with relapsed/refractory B cell non-Hodgkin lymphoma (NHL) or advanced solid tumors and also to identify the recommended Phase 2 dose(s) (RP2Ds) of JNJ-64619178 for NHL and advanced solid tumors (Part 1) and to confirm the tolerability of JNJ-64619178 in participants with lower risk myelodysplastic syndromes (MDS) (Part 2).

NeoplasmsSolid Tumor, AdultNon-Hodgkin Lymphoma+1 more

Janssen Research & Development, LLC114 participantsStarted Jul 2018

Sarasota, Florida, United States • Boston, Massachusetts, United States • Columbus, Ohio, United States +15 more locations

Active Not RecruitingPhase 2< 1 mile

Study of Aspirin in Patients With Vestibular Schwannoma

NCT03079999

This is a phase II prospective, randomized, double-blind, longitudinal study evaluating whether the administration of aspirin can delay or slow tumor growth and maintain or improve hearing in VS patients.

Vestibular SchwannomaAcoustic NeuromaNeurofibromatosis 2

Massachusetts Eye and Ear Infirmary97 participantsStarted Jun 2018

Stanford, California, United States • Miami, Florida, United States • Boston, Massachusetts, United States +2 more locations

A Study of JNJ-64619178, an Inhibitor of PRMT5 in Participants With Advanced Solid Tumors, NHL, and Lower Risk MDS

Study of Aspirin in Patients With Vestibular Schwannoma

Find Trials by Condition in Boston

HELIOS: Open-Label, Long-Term Extension Study to Investigate the Safety, Tolerability, and Efficacy of DISC-1459 (Bitopertin) in Participants With EPP or XLP

Multisite Virtual Reality Intervention for Speech Anxiety

Studying Pathways of Resistance in KRAS-driven Cancers

A Study of Efficacy, Safety, and Tolerability of KAN-101 in People With Celiac Disease

HAELO: A Phase 3 Study to Evaluate NTLA-2002 in Participants With Hereditary Angioedema (HAE)

Electrostimulation Study for Ocular Graft vs. Host Disease

A Study to Assess the Long-Term Safety and Efficacy of Lebrikizumab (LY3650150) in Participants 6 Months to <18 Years of Age With Moderate-to-Severe Atopic Dermatitis

Left Bundle Branch Area Mapping for Conduction System Pacing

DCS Study in Extremely Premature Newborns

Product Performance Report: Evaluate Long-term Reliability & Performance of Medtronic Marketed Cardiac Therapy Products

Point-of-Care AI Assistance and Critical Care Outcomes: A Randomized Trial

SyncAV Post-Market Trial

Study of Cabozantinib in Combination With Atezolizumab Versus Second NHT in Subjects With mCRPC

Study of INBRX-106 and INBRX-106 in Combination With Pembrolizumab (Keytruda®) in Subjects With Locally Advanced or Metastatic Solid Tumors (Hexavalent OX40 Agonist)

Study to Evaluate CCS1477 (Inobrodib) in Haematological Malignancies

An Extension Study for Treatment of Moderately to Severely Active Ulcerative Colitis

A Study to Evaluate the Safety, Pharmacokinetics, Pharmacodynamics, and Antitumor Activity of INV-9956 in Adult Patients With Advanced Metastatic Castration Resistant Prostate Cancer

An Observational LTFU Study for Patients Previously Treated With Autologous ex Vivo Gene Therapy for ADA-SCID