Clinical Trials in Baltimore

Showing 3741-3760 of 20,142 trials

Expanded Access Protocol Using HBOC-201

NCT02684474

The purpose of this protocol is to provide treatment with HBOC-201 to patients with life-threatening anemia for whom allogeneic blood transfusion is not an option. HBOC 201 \[hemoglobin glutamer - 250 (bovine)\] has been previously studied as an alternative to blood transfusions in severely anemic patients needing a way to enhance tissue oxygenation. HBOC-201 is purified, cross-linked and polymerized acellular bovine hemoglobin in a modified lactated Ringer's solution, and does not require blood compatibility.

Anemia

Johns Hopkins University

Baltimore, Maryland, United States

RECRUITING< 1 mile

The Myelin Disorders Biorepository Project

NCT03047369

The Myelin Disorders Biorepository Project (MDBP) seeks to collect and analyze clinical data and biological samples from leukodystrophy patients worldwide to support ongoing and future research projects. The MDBP is one of the world's largest leukodystrophy biorepositories, having enrolled nearly 2,000 affected individuals since it was launched over a decade ago. Researchers working in the biorepository hope to use these materials to uncover new genetic etiologies for various leukodystrophies, develop biomarkers for use in future clinical trials, and better understand the natural history of these disorders. The knowledge gained from these efforts may help improve the diagnostic tools and treatment options available to patients in the future.

LeukodystrophyWhite Matter DiseaseLeukoencephalopathies+63 more

Children's Hospital of Philadelphia12,000 participantsStarted Dec 2016

Los Angeles, California, United States • Orange, California, United States • Palo Alto, California, United States +20 more locations

Expanded Access Protocol Using HBOC-201

The Myelin Disorders Biorepository Project

Find Trials by Condition in Baltimore

Evolocumab in Patients With Acute MI

Tissue Reinforcement for Breast Reconstruction (TRBR) Pivotal Clinical Study (REDEFINE)

A FIH Study of PF-07284890 in Participants With BRAF V600 Mutant Solid Tumors With and Without Brain Involvement

Open Label Extension of Efgartigimod in Adults With Post-COVID-19 POTS

A Study of Enzalutamide Plus Androgen Deprivation Therapy (ADT) Versus Placebo Plus ADT in Patients With Metastatic Hormone Sensitive Prostate Cancer (mHSPC)

TReatment of ADC-Refractory Breast CancEr With Dato-DXd or T-DXd: TRADE DXd

Safety and Efficacy Study of Intracystic TARA-002 for the Treatment of Lymphatic Malformations in Participants 6 Months to Less Than 18 Years of Age

Efficacy and Safety of the CG-100 Intraluminal Bypass Device

An Efficacy, Safety, and Tolerability Study of Veligrotug (VRDN-001), in Participants With Chronic Thyroid Eye Disease (TED) (THRIVE-2)

Aspirin in Preventing Disease Recurrence in Patients With Barrett Esophagus After Successful Elimination by Radiofrequency Ablation

ABTECT-1 - ABX464 Treatment Evaluation for Ulcerative Colitis Therapy -1

Minima Stent System Post- Approval Study (PAS)

A Study of E7386 in Combination With Pembrolizumab in Previously Treated Participants With Selected Solid Tumors

To Evaluate Efficacy of Belinostat or Pralatrexate in Combination Against CHOP Alone in PTCL

EValuating trEatment RESponses of Dupilumab Versus Omalizumab in Type 2 Patients

Non-Operative Management and Early Response Assessment in Rectal Cancer

A Phase 3 Study of Zalunfiban in Subjects With ST-elevation MI

Study of Subcutaneous (SC) Belimumab in Pediatric Participants With Systemic Lupus Erythematosus (SLE)