Clinical Trials in Austin

Showing 12621-12640 of 15,205 trials

A Phase I Study of the Pharmacokinetic Variability and Relative Bioavailability of the Phase 3 and Common Blend Formulations of Eliglustat in Healthy Adult Subjects

NCT01452542

The primary objective of this pilot study is to determine the within-subject pharmacokinetic (PK) variability and relative bioavailability of single oral 150-mg doses of eliglustat administered as the Phase 3 formulation (3x50-mg capsules) and the common blend proposed commercial formulation (1x150-mg capsule) in healthy adult subjects, which will be used to plan and support the design of a subsequent bioequivalence study.

Healthy Volunteer

Genzyme, a Sanofi Company22 participantsStarted Oct 2011

Austin, Texas, United States

COMPLETEDPhase 1< 1 mile

Study to Evaluate the Effect of Eliglustat on the Pharmacokinetics, Safety and Tolerability of Metoprolol in Healthy Adults

NCT01659944

The primary objective is to determine the effect of repeated oral doses of eliglustat 150 mg twice daily (BID) on the pharmacokinetics (PK) of orally administered metoprolol 50 mg in healthy adults. The secondary objective is to assess the safety and tolerability of a single oral dose of metoprolol 50 mg when administered alone and in combination with repeated oral doses of eliglustat 150 mg BID in healthy adults.

Healthy

Genzyme, a Sanofi Company14 participantsStarted May 2012

Austin, Texas, United States

COMPLETEDNA< 1 mile

Feasibility of Telehealth Problem-Solving Therapy for Depressed Homebound Older Adults

NCT00903019

This study will test the feasibility and effectiveness of therapy given via teleconferencing to depressed homebound older adults.

Depression

University of Texas at Austin158 participantsStarted Jun 2009

Austin, Texas, United States

A Phase I Study of the Pharmacokinetic Variability and Relative Bioavailability of the Phase 3 and Common Blend Formulations of Eliglustat in Healthy Adult Subjects

Study to Evaluate the Effect of Eliglustat on the Pharmacokinetics, Safety and Tolerability of Metoprolol in Healthy Adults

Feasibility of Telehealth Problem-Solving Therapy for Depressed Homebound Older Adults

Find Trials by Condition in Austin

Sensitivity of Short and Long Allele Carriers of the 5-HTTLPR to Environmental Threat Post Hydrocortisone Administration

Sitaxsentan Efficacy And Safety Trial With A Randomized Prospective Assessment Of Adding Sildenafil (SR-PAAS)

Study Looking at Combination Therapy (Sitaxsentan+Sildenafil) Vs. Monotherapy (Sitaxsentan Alone) SR-PAAS -Sitaxsentan Efficacy And Safety Trial With A Randomized Prospective Assessment Of Adding Sildenafil

Dialysis Clinical Outcomes Revisited (DCOR) Trial

Clinical Investigation of Expanded Designs of a Multifocal IOL

Study of Plerixafor Combined With Cytarabine and Daunorubicin in Patients With Newly Diagnosed Acute Myeloid Leukemia

Clinical Trial to Evaluate the Efficacy and Safety of Fesoterodine in Comparison to Tolterodine for Overactive Bladder (OAB)

Rituximab in Renal Allograft Recipients Who Develop Early De Novo Anti-HLA Alloantibodies

A Randomized, Double Blind Trial of LdT (Telbivudine) Versus Lamivudine in Adults With Compensated Chronic Hepatitis B

A Phase 4, Conversion Study of Hectorol® Injection to Hectorol® Capsules in Stage 5 CKD Patients on Dialysis

An Open-label, Prospective, Randomized, Multi-center, Phase II Comparative Trial of Thymoglobulin Versus Simulect for the Prevention of Delayed Graft Function and Acute Allograft Rejection in Renal Allograft Recipients.

Efficacy and Safety Study of Abatacept to Treat Lupus Nephritis

Fibroid Ablation Study - Large Fibroids

Phase IIIB Subcutaneous Abatacept Monotherapy Study

Effects of HQK-1001 in Patients With Sickle Cell Disease

The BRILLIANT Study

Short Course vs. Standard Course Radiotherapy in Elderly and/or Frail Patients With Glioblastoma Multiforme